SynthesisBioMed research international2014
Clinical applications of platelet-rich plasma in patellar tendinopathy.
Synthesis in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Is Platelet-rich Plasma Injection Effective for Chronic Achilles Tendinopathy? A Meta-analysis.Clinical orthopaedics and related research · 2018Pooled it
- Effect of platelet-rich plasma on the degenerative rotator cuff tendinopathy according to the compositions.Journal of orthopaedic surgery and research · 2019Trial
- Review
- Effect of a single versus serial platelet-rich plasma injection on the healing of acute patellar tendon defect: an experimental study.BMC musculoskeletal disorders · 2024Article
- Clinical Study on the treatment of chronic infectious ulcers using Platelet-Rich technology combined with moist dressings.Pakistan journal of medical sciences · 2024Article
- Curcumin Improves Functional Recovery of Ruptured Tendon by Promoting Tenogenesis via PI3K/Akt Signaling.Stem cells translational medicine · 2024Article
- Review
- Platelet-rich plasma injection in the treatment of patellar tendinopathy: a systematic review and meta-analysis.Knee surgery & related research · 2022Review
- Effects of leukocyte- and platelet-rich plasma on tendon disorders based onExperimental and therapeutic medicine · 2021Review
- Proposal for a Clinical Analysis of Patellar Tendon Pathologies: In Search of Efficient Therapeutic Indications.Orthopaedic journal of sports medicine · 2020Article
- Platelet Concentrates in Musculoskeletal Medicine.International journal of molecular sciences · 2020Review
- The Effectiveness of Minimally Invasive Techniques in the Treatment of Patellar Tendinopathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Role of a combination dietary supplement containing mucopolysaccharides, vitamin C, and collagen on tendon healing in rats.Acta orthopaedica et traumatologica turcica · 2018Article
- Platelet-rich Plasma for Skin Rejuvenation and Treatment of Actinic Elastosis in the Lower Eyelid Area.Cureus · 2018Article
- Nonoperative treatment of muscle injuries - recommendations from the GOTS expert meeting.Journal of experimental orthopaedics · 2018Review
- Platelet-rich plasma (PRP) for knee disorders.EFORT open reviews · 2017Review
- Application of Tendon Stem/Progenitor Cells and Platelet-Rich Plasma to Treat Tendon Injuries.Operative techniques in orthopaedics · 2016Article
- Platelet-rich plasma versus open surgical release in chronic tennis elbow: A retrospective comparative study.Journal of orthopaedics · 2016Article
- Differences in glutamate receptors and inflammatory cell numbers are associated with the resolution of pain in human rotator cuff tendinopathy.Arthritis research & therapy · 2015Article
- Tendon injury: from biology to tendon repair.Nature reviews. Rheumatology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Platelet-rich plasma (PRP), a blood derivative with high concentrations of platelets, has been found to have high levels of autologous growth factors (GFs), such as transforming growth factor-β (TGF-β), platelet-derived growth factor (PDGF), fibroblastic growth factor (FGF), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF). These GFs and other biological active proteins of PRP can promote tissue healing through the regulation of fibrosis and angiogenesis. Moreover, PRP is considered to be safe due to its autologous nature and long-term usage without any reported major complications. Therefore, PRP therapy could be an option in treating overused tendon damage such as chronic tendinopathy. Here, we present a systematic review highlighting the clinical effectiveness of PRP injection therapy in patellar tendinopathy, which is a major cause of athletes to retire from their respective careers.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.