Evidence map›Paper›PMID 25136546›Full record

ReviewFrontiers in pediatrics2014

Focus on apoptosis to decipher how alcohol and many other drugs disrupt brain development.

John W Olney

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Defects of Cortical Microcircuits Following Early Exposure to Alcohol.Advances in experimental medicine and biology · 2025
    Review
  2. Article
  3. Article
  4. Mechanisms of Ethanol-Induced Cerebellar Ataxia: Underpinnings of Neuronal Death in the Cerebellum.International journal of environmental research and public health · 2021
    Review
  5. Article
  6. Article
  7. Alcohol and the Developing Brain: Why Neurons Die and How Survivors Change.International journal of molecular sciences · 2018
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

John W OlneyDepartment of Psychiatry, Washington University School of Medicine , St. Louis, MO , USA.
Washington University in St. Louis · US

Funding

Washington University Intellectual and Developmental Disabilities Research CenterP30HD062171 · NICHD · WASHINGTON UNIVERSITY · PI INDER, TERRIE E · 2010 to 2014
$4.3M
ANESTHESIA TOXICITY IN NEONATAL PRIMATE BRAINR01HD052664 · NICHD · WASHINGTON UNIVERSITY · PI NOGUCHI, KEVIN K · 2007 to 2016
$4.0M
PCP, SIGMA OPIATES, AND GLUTAMERGIC TRANSMISSIONR01DA005072 · NIDA · WASHINGTON UNIVERSITY · PI OLNEY, JOHN W · 1987 to 2010
$3.4M
Acute Brain Injury, Mechanisms and ConsequencesR37HD037100 · NICHD · WASHINGTON UNIVERSITY · PI OLNEY, JOHN W · 2002 to 2011
$3.2M
ACUTE BRAIN INJURY, MECHANISMS AND PROTECTIONR01HD037100 · NICHD · WASHINGTON UNIVERSITY · PI OLNEY, JOHN W · 1999 to 2001
$439k
NICHD NIH HHS P30 HD062171NICHD NIH HHS R01 HD037100NICHD NIH HHS R01 HD052664NICHD NIH HHS R37 HD037100NIDA NIH HHS R01 DA005072
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alcoholanestheticsanti-epilepticsapoptosisdeveloping brainneuronsoligodendrocytessedatives

Identifiers

PMID25136546
PMCPMC4120674
OpenAlexW1975521055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.