Evidence map›Paper›PMID 25136423›Full record

ArticleJournal of clinical and experimental dentistry2014

Estimation of serum lipids in patients with Oral Submucous Fibrosis in India.

Kratika Ajai, Sunil R Panat, Ashish Aggarwal, Nupur Agarwal, Nitin Upadhyay, Anuja Joshi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Unveiling Lipid Metabolic Shifts in Different Stages of Oral Submucous Fibrosis: A New Horizon in Predicting Malignant Transformation.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  3. Alteration of Serum Lipid in Oral Sub Mucous Fibrosis in Central India.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kratika AjaiPost Graduate Student. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bareilly, UP, India.
Sunil R PanatProfessor and Head. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bareilly, UP, India.
Ashish AggarwalSenior Lecturer. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bareilly, UP, India.
Nupur AgarwalSenior Lecturer. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bareilly, UP, India.
Nitin UpadhyaySenior Lecturer. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bareilly, UP, India.
Anuja JoshiPost Graduate Student. Department of Oral Medicine and Radiology, Institute of Dental Sciences, Bareilly, UP, India.
Sardar Patel Post Graduate Institute of Dental and Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOral submucous fibrosis (OSMF) is the most prevalent precancerous condition in India. Low levels of lipids serves as a marker and prognostic indicator in the early detection of oral precancerous and cancerous states. In spite of the high prevalence and its potential to undergo malignant transformation, this condition has not widely been investigated with respect to the serum lipid levels. In the present study, an attempt was made to analyze the complete serum lipid profile, total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol and very low density lipoprotein (VLDL) cholesterol in OSMF and controls. MATERIAL AND

methodsThe study was conducted in 45 clinically and histopathologically diagnosed cases of OSMF and 45 age and sex matched controls. The complete lipid profile including TC, TG, HDL cholesterol, LDL cholesterol and VLDL cholesterol was analyzed.

resultsThe serum lipid levels were significantly lower in the patients with OSMF than in the controls. When the values were compared between different disease stages, the maximum reduction of lipids was evident for stage 3 OSMF. From the present results, it is evident that the level of serum lipids decreases with progression of the disease.

conclusionsFrom these findings, it appears that the decrease in the lipid levels may be considered as a useful marker in the early diagnosis of oral premalignant condition like OSMF. Key words:Oral submucous fibrosis, lipids, premalignant condition.

Identifiers

PMID25136423
PMCPMC4134851
OpenAlexW2134887825

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.