ReviewSystems and synthetic biology2014
Divided we stand: splitting synthetic cells for their proliferation.
Review in Systems and synthetic biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Hydration gradients drive lipid self-segregation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Biomimetic Materials to Fabricate Artificial Cells.Chemical reviews · 2024Review
- Intravesicular Solute Delivery and Surface Area Regulation in Giant Unilamellar Vesicles Driven by Cycles of Osmotic Stresses.Journal of the American Chemical Society · 2024Article
- Environmental Stability and Its Importance for the Emergence of Darwinian Evolution.Life (Basel, Switzerland) · 2023Article
- Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many.ACS synthetic biology · 2023Review
- Shape Deformation, Budding and Division of Giant Vesicles and Artificial Cells: A Review.Life (Basel, Switzerland) · 2022Review
- Vesicles Balance Osmotic Stress with Bending Energy That Can Be Released to Form Daughter Vesicles.The journal of physical chemistry letters · 2022Article
- Synthesis of lipid membranes for artificial cells.Nature reviews. Chemistry · 2021Review
- Towards a synthetic cell cycle.Nature communications · 2021Review
- Division and Regrowth of Phase-Separated Giant Unilamellar Vesicles*.Angewandte Chemie (International ed. in English) · 2021Article
- Modularize and Unite: Toward Creating a Functional Artificial Cell.Frontiers in molecular biosciences · 2021Review
- Geometric principles underlying the proliferation of a model cell system.Nature communications · 2020Article
- Synthetic Minimal Cell: Self-Reproduction of the Boundary Layer.ACS omega · 2019Article
- On-chip microfluidic production of cell-sized liposomes.Nature protocols · 2018Article
- Mechanical Division of Cell-Sized Liposomes.ACS nano · 2018Article
- Growing Membranes In Vitro by Continuous Phospholipid Biosynthesis from Free Fatty Acids.ACS synthetic biology · 2018Article
- Dividing the Archaeal Way: The Ancient Cdv Cell-Division Machinery.Frontiers in microbiology · 2018Review
- Interrupting peptidoglycan deacetylation during Bdellovibrio predator-prey interaction prevents ultimate destruction of prey wall, liberating bacterial-ghosts.Scientific reports · 2016Article
- Octanol-assisted liposome assembly on chip.Nature communications · 2016Article
- Engineering protocells: prospects for self-assembly and nanoscale production-lines.Life (Basel, Switzerland) · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the recent dawn of synthetic biology, the old idea of man-made artificial life has gained renewed interest. In the context of a bottom-up approach, this entails the de novo construction of synthetic cells that can autonomously sustain themselves and proliferate. Reproduction of a synthetic cell involves the synthesis of its inner content, replication of its information module, and growth and division of its shell. Theoretical and experimental analysis of natural cells shows that, whereas the core synthesis machinery of the information module is highly conserved, a wide range of solutions have been realized in order to accomplish division. It is therefore to be expected that there are multiple ways to engineer division of synthetic cells. Here we survey the field and review potential routes that can be explored to accomplish the division of bottom-up designed synthetic cells. We cover a range of complexities from simple abiotic mechanisms involving splitting of lipid-membrane-encapsulated vesicles due to physical or chemical principles, to potential division mechanisms of synthetic cells that are based on prokaryotic division machineries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.