ArticleFrontiers in human neuroscience2014
Functional MRI activation in white matter during the Symbol Digit Modalities Test.
Article in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Information processing speed modulation by electrical brain stimulation in multiple sclerosis: towards individually tailored protocols.Brain communications · 2025Trial
- Altered Topological Properties of White-Matter Functional Networks in Young Smokers.Addiction biology · 2026Article
- BrainVAE: Exploring the role of white matter BOLD in preclinical Alzheimer's disease classification.bioRxiv : the preprint server for biology · 2025Article
- Association of microstructural lesions of the corpus callosum with cognitive impairment in patients with high grade glioma.Acta neurochirurgica · 2025Article
- Sex differences in patterns of white matter neuroplasticity after balance training in young adults.Frontiers in human neuroscience · 2024Article
- Theta burst stimulation on the fronto-cerebellar connective network promotes cognitive processing speed in the simple cognitive task.Frontiers in human neuroscience · 2024Article
- Mapping white matter structural covariance connectivity for single subject using wavelet transform with T1-weighted anatomical brain MRI.Frontiers in neuroscience · 2022Article
- Vascular Cognitive Impairment After Mild Stroke: Connectomic Insights, Neuroimaging, and Knowledge Translation.Frontiers in neuroscience · 2022Review
- Function-structure coupling: White matter functional magnetic resonance imaging hyper-activation associates with structural integrity reductions in schizophrenia.Human brain mapping · 2021Article
- Acute Effects of a Perturbation-Based Balance Training on Cognitive Performance in Healthy Older Adults: A Pilot Study.Frontiers in sports and active living · 2021Article
- A neuromarker of individual general fluid intelligence from the white-matter functional connectome.Translational psychiatry · 2020Article
- White Matter Neuroplasticity: Motor Learning Activates the Internal Capsule and Reduces Hemodynamic Response Variability.Frontiers in human neuroscience · 2020Article
- Exploring the functional connectome in white matter.Human brain mapping · 2019Article
- Regional and network properties of white matter function in Parkinson's disease.Human brain mapping · 2019Article
- White Matter fMRI Activation Cannot Be Treated as a Nuisance Regressor: Overcoming a Historical Blind Spot.Frontiers in neuroscience · 2019Article
- Altered Resting State Functional Activity and Microstructure of the White Matter in Migraine With Aura.Frontiers in neurology · 2019Article
- Robust Motion Regression of Resting-State Data Using a Convolutional Neural Network Model.Frontiers in neuroscience · 2019Article
- Article
- Visualizing functional pathways in the human brain using correlation tensors and magnetic resonance imaging.Magnetic resonance imaging · 2016Article
- Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly.Anesthesiology clinics · 2015Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent evidence shows that functional magnetic resonance imaging (fMRI) can detect activation in white matter (WM). Such advances have important implications for understanding WM dysfunction. A key step in linking neuroimaging advances to the evaluation of clinical disorders is to examine whether WM activation can be detected at the individual level during clinical tests associated with WM function. We used an adapted Symbol Digit Modalities Test (SDMT) in a 4T fMRI study of healthy adults.
resultsRESULTS from 17 healthy individuals revealed WM activation in 88% of participants (15/17). The activation was in either the corpus callosum (anterior and/or posterior) or internal capsule (left and/or right).
conclusionsThe findings link advances in fMRI to an established clinical test of WM function. Future work should focus on evaluating patients with WM dysfunction.
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