ArticleInternational archives of occupational and environmental health2015
Mortality from internal and external radiation exposure in a cohort of male German uranium millers, 1946-2008.
Article in International archives of occupational and environmental health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 6 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 6 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Radon exposure and potential health effects other than lung cancer: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Exposure to low-dose radiation in occupational settings and ischaemic heart disease: a systematic review and meta-analysis.Occupational and environmental medicine · 2023Pooled it
- Deep Breaths: A Systematic Review of the Potential Effects of Employment in the Nuclear Industry on Mortality from Non-Malignant Respiratory Disease.Radiation research · 2022Pooled it
- Radon exposure and risk of cerebrovascular disease: a systematic review and meta-analysis in occupational and general population studies.Environmental science and pollution research international · 2022Pooled it
- Exposure to Residential Radon and COPD: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2020Pooled it
- Occupational exposure to respirable crystalline silica and chronic non-malignant renal disease: systematic review and meta-analysis.International archives of occupational and environmental health · 2017Pooled it
- Updated Knowledge on Radon Exposure: Quantification Methods, Health Effects, and Molecular Mechanisms.Environment & health (Washington, D.C.) · 2026Review
- Extracellular vesicle proteomic expression is influenced by mining tenure in former uranium miners.Environmental research · 2025Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Low-Dose Occupational Exposure to Ionizing Radiation and Cardiovascular Effects: A Narrative Review.Healthcare (Basel, Switzerland) · 2024Review
- Analysis of genetic instability induced by radon exposure in iron mine processing workers in Shandong Province, Northern China.Frontiers in public health · 2024Article
- Third mortality follow-up of the Mallinckrodt uranium processing workers, 1942-2019.International journal of radiation biology · 2024Article
- Health Effects of Particulate Uranium Exposure.Toxics · 2022Review
- Brain cancer incidence rates and the presence of nuclear reactors in US states: a hypothesis-generating study.Environmental geochemistry and health · 2021Article
- On the choice of methodology for evaluating dose-rate effects on radiation-related cancer risks.Radiation and environmental biophysics · 2021Article
- Cohort profile: four early uranium processing facilities in the US and Canada.International journal of radiation biology · 2021Article
- Dose limits for occupational exposure to ionising radiation and genotoxic carcinogens: a German perspective.Radiation and environmental biophysics · 2020Review
- Radiation Dosimetry of Inhaled Radioactive Aerosols: CFPD and MCNP Transport Simulations of Radionuclides in the Lung.Scientific reports · 2019Article
- Health Effects of Radon Exposure.Yonsei medical journal · 2019Review
- Low-dose ionizing radiation increases the mortality risk of solid cancers in nuclear industry workers: A meta-analysis.Molecular and clinical oncology · 2018Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo examine exposure-response relationships between ionizing radiation and several mortality outcomes in a subgroup of 4,054 men of the German uranium miner cohort study, who worked between 1946 and 1989 in milling facilities, but never underground or in open pit mines.
methodsMortality follow-up was from 1946 to 2008, accumulating 158,383 person-years at risk. Cumulative exposure to radon progeny in working level months (WLM) (mean = 8, max = 127), long-lived radionuclides from uranium ore dust in kBqh/m(3) (mean = 3.9, max = 132), external gamma radiation in mSv (mean = 26, max = 667) and silica dust was estimated by a comprehensive job-exposure matrix. Internal Poisson regression models were applied to estimate the linear excess relative risk (ERR) per unit of cumulative exposure.
resultsOverall, a total of 457, 717 and 111 deaths occurred from malignant cancer, cardiovascular diseases and non-malignant respiratory diseases, respectively. Uranium ore dust and silica dust were not associated with mortality from any of these disease groups. A statistically significant relationship between cumulative radon exposure and mortality from all cancers (ERR/100 WLM = 1.71; p = 0.02), primarily due to lung cancer (n = 159; ERR/100 WLM = 3.39; p = 0.05), was found. With respect to cumulative external gamma radiation, an excess of mortality of solid cancers (n = 434; ERR/Sv = 1.86; p = 0.06), primarily due to stomach cancer (n = 49, ERR/Sv = 10.0; p = 0.12), was present.
conclusionThe present findings show an excess mortality from lung cancer due to radon exposure and from solid cancers due to external gamma radiation in uranium millers that was not statistically significant. Exposure to uranium was not associated with any cause of death, but absorbed organ doses were estimated to be low.
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