Evidence map›Paper›PMID 25135842›Full record

ArticleJournal of community health2014

Strategies for hepatitis C testing and linkage to care for vulnerable populations: point-of-care and standard HCV testing in a mobile medical clinic.

Jamie P Morano, Alexei Zelenev, Andrea Lombard, Ruthanne Marcus, Britton A Gibson, Frederick L Altice

Open access · greenAbstract read
In one paragraph

Article in Journal of community health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jamie P MoranoAIDS Program, Section of Infectious Diseases, Department of Medicine, Yale University School of Medicine, 135 College Street, Suite 323, New Haven, CT, 06510, USA, jamie.morano@yale.edu.
Alexei Zelenev
Andrea Lombard
Ruthanne Marcus
Britton A Gibson
Frederick L Altice
Yale University · USConnecticut Department of Public Health · US

Funding

Direct/Observed Therapy/Community-Released HIV+PrisonersR01DA017059 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2004 to 2008
$3.3M
DIRECTLY OBSERVED ANTI RETROVIRAL THERAPY AMONG ACTIVE DR01DA013805 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2000 to 2004
$2.1M
Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
PROVISION OF NEEDLE EXCHANGE BASED HEALTH SERVICESR01DA010186 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 1995 to 1999
–
NIDA NIH HHS K24 DA017072NIDA NIH HHS R01 DA013805NIDA NIH HHS R01 DA017059NIDA NIH HHS R01 DA13805PHS HHS T32 A1007517
6 · The paper itself

Abstract

Despite new Hepatitis C virus (HCV) therapeutic advances, challenges remain for HCV testing and linking patients to care. A point-of-care (POC) HCV antibody testing strategy was compared to traditional serological testing to determine patient preferences for type of testing and linkage to treatment in an innovative mobile medical clinic (MMC). From 2012 to 2013, all 1,345 MMC clients in New Haven, CT underwent a routine health assessment, including for HCV. Based on patient preferences, clients could select between standard phlebotomy or POC HCV testing, with results available in approximately 1 week versus 20 min, respectively. Outcomes included: (1) accepting HCV testing; (2) preference for rapid POC HCV testing; and (3) linkage to HCV care. All clients with reactive test results were referred to a HCV specialty clinic. Among the 438 (32.6 %) clients accepting HCV testing, HCV prevalence was 6.2 % (N = 27), and 209 (47.7 %) preferred POC testing. Significant correlates of accepting HCV testing was lower for the "baby boomer" generation (AOR 0.67; 95 % CI 0.46-0.97) and white race (AOR 0.55; 95 % CI 0.36-0.78) and higher for having had a prior STI diagnosis (AOR 5.03; 95 % CI 1.76-14.26), prior injection drug use (AOR 2.21; 95 % CI 1.12-4.46), and being US-born (AOR 1.76; 95 % CI 1.25-2.46). Those diagnosed with HCV and preferring POC testing (N = 16) were significantly more likely than those choosing standard testing (N = 11) to be linked to HCV care within 30 days (93.8 vs. 18.2 %; p < 0.0001). HCV testing is feasible in MMCs. While patients equally preferred POC and standard HCV testing strategies, HCV-infected patients choosing POC testing were significantly more likely to be linked to HCV treatment. Important differences in risk and background were associated with type of HCV testing strategy selected. HCV testing strategies should be balanced based on costs, convenience, and ability to link to HCV treatment.

Indexed as

Mobile Health UnitsPoint-of-Care SystemsVulnerable PopulationsAdultConnecticutFemaleHepatitis CHumansMalePatient Acceptance of Health CarePhlebotomy

Identifiers

PMID25135842
PMCPMC8317466
OpenAlexW1965388675

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.