ArticleJournal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban2014
Expression profiling of microRNAs in hippocampus of rats following traumatic brain injury.
Article in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Acute Spinal Cord Injury: A Systematic Review Investigating miRNA Families Involved.International journal of molecular sciences · 2019Pooled it
- Extracellular Vesicle and Plasma miRNAs as Candidate Biomarkers of Traumatic Brain Injury in the Context of Polytrauma.International journal of molecular sciences · 2026Article
- MiR338-3p expression in extracellular vesicles after severe trauma with or without traumatic brain injury.Brain communications · 2025Article
- Noncoding RNA crosstalk in brain health and diseases.Neurochemistry international · 2021Review
- Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation.Brain pathology (Zurich, Switzerland) · 2020Article
- microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.Journal of neurochemistry · 2020Article
- Integrated Bioinformatics Analysis for the Identification of Key Molecules and Pathways in the Hippocampus of Rats After Traumatic Brain Injury.Neurochemical research · 2020Article
- Chronic Regulation of miR-124-3p in the Perilesional Cortex after Experimental and Human TBI.International journal of molecular sciences · 2020Article
- Epigenetic mechanisms of neurodegenerative diseases and acute brain injury.Neurochemistry international · 2020Review
- MicroRNAs: The New Challenge for Traumatic Brain Injury Diagnosis.Current neuropharmacology · 2020Review
- Plasma Exosome-derived MicroRNAs as Novel Biomarkers of Traumatic Brain Injury in Rats.International journal of medical sciences · 2020Article
- Current trends in biomarker discovery and analysis tools for traumatic brain injury.Journal of biological engineering · 2019Review
- Clinical-pathological study on β-APP, IL-1β, GFAP, NFL, Spectrin II, 8OHdG, TUNEL, miR-21, miR-16, miR-92 expressions to verify DAI-diagnosis, grade and prognosis.Scientific reports · 2018Article
- MicroRNA Signature of Traumatic Brain Injury: From the Biomarker Discovery to the Point-of-Care.Frontiers in neurology · 2018Review
- MicroRNAs as diagnostic markers and therapeutic targets for traumatic brain injury.Neural regeneration research · 2017Review
- MiR-144 promotes β-amyloid accumulation-induced cognitive impairments by targeting ADAM10 following traumatic brain injury.Oncotarget · 2017Article
- Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect.Frontiers in molecular neuroscience · 2017Article
- Traumatic brain injury increases levels of miR-21 in extracellular vesicles: implications for neuroinflammation.FEBS open bio · 2016Article
- Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury.Experimental neurology · 2015Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The changes of microRNA expression in rat hippocampus after traumatic brain injury (TBI) were explored. Adult SD rats received a single controlled cortical impact injury, and the ipsilateral hippocampus was harvested for the subsequent microarray assay at three time points after TBI: 1st day, 3rd day and 5th day, respectively. We characterized the microRNA expression profile in rat hippocampus using the microRNA microarray analysis, and further verified microarray results of miR-142-3p and miR-221 using quantitative real-time PCR. Totally 205 microRNAs were identified and up-/down-regulated more than 1.5 times. There were significant changes in 17 microRNAs at all three time points post-TBI. The quantitative real-time PCR results of miR-142-3p and miR-221 indicated good consistency with the results of the microarray method. MicroRNAs altered at different time points post-TBI. MiR-142-3p and miR-221 may be used as potentially biological markers for TBI assessment in forensic practice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.