ArticlePediatric nephrology (Berlin, Germany)2015
Indications, technique, and outcome of therapeutic apheresis in European pediatric nephrology units.
Article in Pediatric nephrology (Berlin, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 55 citations in OpenAlex.
- Evolution of Therapeutic Plasma Exchange Use and Outcomes in Children Across American Society for Apheresis Categories: A Single-Center Cohort Study.Journal of clinical apheresis · 2026Article
- Treatment of Focal Segmental Glomerulosclerosis in Low- and Middle-Income Countries: Emerging Extracorporeal Therapies.Blood purification · 2026Review
- Safety and Efficacy of Therapeutic Plasma Exchange in Pediatric Non-Neurological Diseases.International journal of nephrology and renovascular disease · 2026Article
- Therapeutic apheresis: is it safe in children with kidney disease?Pediatric nephrology (Berlin, Germany) · 2024Article
- Therapeutic plasma exchange in paediatric nephrology in Ireland.Irish journal of medical science · 2024Article
- Efficacy and Safety of Therapeutic Plasma Exchange in Children with Neuroimmunological Disorders: A Limited Unicentral Study.Iranian journal of child neurology · 2024Article
- Double filtration plasmapheresis for children with different types of critical kidney diseases: a single-center retrospective cohort study.Translational pediatrics · 2023Article
- Near-fatal cocaine intoxication in an infant with thrombotic microangiopathy associated with multiple organ failure.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023Article
- [Therapeutic plasma exchange in the pediatric intensive care unit: a single-center retrospective study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Safety of Therapeutic Apheresis in Children and Adolescents.Frontiers in pediatrics · 2022Article
- Therapeutic Plasma Exchange in Pediatric Intensive Care Unit: A Single-center Experience.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
- Therapeutic plasma exchange: single-center experience in children with kidney disorders.Pediatric nephrology (Berlin, Germany) · 2021Article
- Combination of plasma exchange and haemofiltration for treating thrombotic microangiopathy in children.The Journal of international medical research · 2020Article
- Complications of therapeutic plasma exchange: A retrospective study of 1201 procedures in 435 children.Medicine · 2019Article
- Hemolytic uremic syndrome in a developing country: Consensus guidelines.Pediatric nephrology (Berlin, Germany) · 2019Article
- Complications of Therapeutic Plasma Exchange in pediatric patients: An experience at a tertiary care hospital.Pakistan journal of medical sciencesArticle
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Authors and funding
18 authors at 13 institutions in 12 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew observations on apheresis in pediatric nephrology units have been published.
methodsThis retrospective study involved children ≤18 years undergoing plasma exchange (PE), immunoadsorption (IA), or double filtration plasmapheresis (DFPP) in 12 European pediatric nephrology units during 2012.
resultsSixty-seven children underwent PE, ten IA, and three DFPP, for a total of 738 PE and 349 IA/DFPP sessions; 67.2 % of PE and 69.2 % of IA/DFPP patients were treated for renal diseases, in particular focal segmental glomerulosclerosis (FSGS), hemolytic-uremic syndrome (HUS), and human leukocyte antigen (HLA) desensitization prior to renal transplantation; 20.9 % of PE and 23.1 % of IA/DFPP patients had neurological diseases. Membrane filtration was the most common technique, albumin the most frequently used substitution fluid, and heparin the preferred anticoagulant. PE achieved full disease remission in 25 patients (37.3 %), partial remission in 22 (32.8 %), and had no effect in 20 (29.9 %). The response to IA/DFPP was complete in seven patients (53.8 %), partial in five (38.5 %), and absent in one (7.7 %). Minor adverse events occurred during 6.9 % of PE and 9.7 % of IA/DFPP sessions.
conclusionsPE, IA, and DFPP are safe apheresis methods in children. Efficacy is high in pediatric patients with recurrent focal segmental glomerulosclerosis (FSGS), atypical hemolytic uremic syndrome (HUS), human leukocyte antigen (HLA) sensitization, and neurological autoimmune diseases.
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