ArticleCell stress & chaperones2015
Isolation of arginine kinase from Apis cerana cerana and its possible involvement in response to adverse stress.
Article in Cell stress & chaperones, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 43 citations in OpenAlex.
- Deformed wing virus coopts the host arginine kinase to enhance its fitness in honey bees (Apis mellifera).BMC biology · 2025Article
- A comprehensive review of arginine kinase proteins: What we need to know?Biochemistry and biophysics reports · 2024Review
- Crystal Structure of H227A Mutant of Arginine Kinase inMolecules (Basel, Switzerland) · 2022Article
- Immunomodulatory effects of two recombinant arginine kinases inFrontiers in immunology · 2022Article
- Cloning and expression studies on glutathione S-transferase like-gene in honey bee for its role in oxidative stress.Cell stress & chaperones · 2021Article
- Broad-complex transcription factor mediates opposing hormonal regulation of two phylogenetically distant arginine kinase genes in Tribolium castaneum.Communications biology · 2020Article
- Apoferritin and Apoferritin-Capped Metal Nanoparticles Inhibit Arginine Kinase ofMolecules (Basel, Switzerland) · 2020Article
- Identification of an Apis cerana cerana MAP kinase phosphatase 3 gene (AccMKP3) in response to environmental stress.Cell stress & chaperones · 2019Article
- Identification of an inositol-3-phosphate synthase 1-B gene (AccIPS1-B) from Apis cerana cerana and its role in abiotic stress.Cell stress & chaperones · 2019Article
- Role of AccMGST1 in oxidative stress resistance in Apis cerana cerana.Cell stress & chaperones · 2019Article
- Two Phytoplasmas Elicit Different Responses in the Insect Vector Euscelidius variegatus Kirschbaum.Infection and immunity · 2018Article
- Identification of a melatonin receptor type 1A gene (AccMTNR1A) in Apis cerana cerana and its possible involvement in the response to low temperature stress.Die Naturwissenschaften · 2018Article
- Identification, Expression, and Regulation of an Omega Class Glutathione S-transferase inFrontiers in physiology · 2018Article
- Environmental Stress Responses ofFrontiers in genetics · 2018Article
- Proteomic analysis in the Dufour's gland of Africanized Apis mellifera workers (Hymenoptera: Apidae).PloS one · 2017Article
- A typical RNA-binding protein gene (AccRBM11) in Apis cerana cerana: characterization of AccRBM11 and its possible involvement in development and stress responses.Cell stress & chaperones · 2016Article
- A glutathione S-transferase gene associated with antioxidant properties isolated from Apis cerana cerana.Die Naturwissenschaften · 2016Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arginine kinases (AK) in invertebrates play the same role as creatine kinases in vertebrates. Both proteins are important for energy metabolism, and previous studies on AK focused on this attribute. In this study, the arginine kinase gene was isolated from Apis cerana cerana and was named AccAK. A 5'-flanking region was also cloned and shown to contain abundant putative binding sites for transcription factors related to development and response to adverse stress. We imitated several abiotic and biotic stresses suffered by A. cerana cerana during their life, including heavy metals, pesticides, herbicides, heat, cold, oxidants, antioxidants, ecdysone, and Ascosphaera apis and then studied the expression patterns of AccAK after these treatments. AccAK was upregulated under all conditions, and, in some conditions, this response was very pronounced. Western blot and AccAK enzyme activity assays confirmed the results. In addition, a disc diffusion assay showed that overexpression of AccAK reduced the resistance of Escherichia coli cells to multiple adverse stresses. Taken together, our results indicated that AccAK may be involved of great significance in response to adverse abiotic and biotic stresses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.