Evidence map›Paper›PMID 25135120›Full record

ArticleBMC oral health2014

Clinicopathological characteristics of oral squamous cell carcinoma in Northern Norway: a retrospective study.

Oddveig G Rikardsen, Inger-Heidi Bjerkli, Lars Uhlin-Hansen, Elin Hadler-Olsen, Sonja E Steigen

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  10. Role of Inflammatory Markers in Prognosis of Oral Squamous Cell Carcinoma.Asian Pacific journal of cancer prevention : APJCP · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oddveig G Rikardsen
Inger-Heidi Bjerkli
Lars Uhlin-Hansen
Elin Hadler-Olsen
Sonja E SteigenDepartment of Medical Biology - Tumour Biology Research Group, UiT The Arctic University of Norway, Tromsø, Norway. sonja.steigen@unn.no.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe main aim of the study was to evaluate if patients with oral squamous carcinomas in Northern Norway differ from patients in other countries with regard to clinicopathological characteristics and also study the influence of risk factors. Such a comparison is of demographical interest, and also important for the interpretation of result from studies on prognostic biomarkers.

methodsWe describe clinicopathological characteristics of 133 North Norwegian patients diagnosed with squamous cell carcinoma of the oral cavity in the period 1986-2002, and evaluate the significance of different risk factors.

resultsThe cohort consisted of 69 men and 64 women, giving male/female ratio of 1.1. Forty-seven of the 133 patients (35%) died of the disease within 5 years from diagnosis. There was no significant difference between the genders concerning time to disease specific death, even though men both smoked and drank more alcohol than women. As expected, the strongest predictors for disease specific death were tumour size and the presence of regional lymph node metastasis. We also found that heavy smokers and drinkers presented with more advanced disease, more often localized to the floor of mouth compared to non-smoking and abstinent patients, who more often presented with tumours of the mobile tongue.

conclusionsOur results correlate well with previously published clinicopathological data on comparable cohorts, which is important when considering the applicability of results from biomarker studies performed on this material compared to other cohorts, and vice versa.

Indexed as

AdultAgedAged, 80 and overAlcohol DrinkingCarcinoma, Squamous CellCohort StudiesCyclin-Dependent Kinase Inhibitor p16FemaleHumansLymphatic MetastasisMaleMiddle AgedMouth FloorMouth NeoplasmsNeoplasm StagingNorwayCyclin-Dependent Kinase Inhibitor p16

Identifiers

PMID25135120
PMCPMC4149799

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.