ArticleScientific reports2014
Graphene oxide amplifies the phytotoxicity of arsenic in wheat.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 160 citations in OpenAlex.
- Effects of Graphene Oxide on Phosphorus Uptake in the Arbuscular Mycorrhizal Symbiosis ofPlants (Basel, Switzerland) · 2026Article
- Ameliorating Effects of Graphene Oxide on Cadmium Accumulation and Eco-Physiological Characteristics in a Greening Hyperaccumulator (Plants (Basel, Switzerland) · 2023Article
- Impact of secondary salts, temperature, and pH on the colloidal stability of graphene oxide in water.Nanoscale advances · 2022Article
- Graphene Oxide, a Novel Nanomaterial as Soil Water Retention Agent, Dramatically Enhances Drought Stress Tolerance in Soybean Plants.Frontiers in plant science · 2022Article
- Enhanced tolerance to salinity stress in grapevine plants through application of carbon quantum dots functionalized by proline.Environmental science and pollution research international · 2021Article
- Nanotechnology and artificial intelligence to enable sustainable and precision agriculture.Nature plants · 2021Review
- Combined effects of carbon nanotubes and cadmium on the photosynthetic capacity and antioxidant response of wheat seedlings.Environmental science and pollution research international · 2021Article
- Status Quo in Data Availability and Predictive Models of Nano-Mixture Toxicity.Nanomaterials (Basel, Switzerland) · 2021Review
- Effects of graphene on morphology, microstructure and transcriptomic profiling of Pinus tabuliformis Carr. roots.PloS one · 2021Article
- Nanoparticles in Agroindustry: Applications, Toxicity, Challenges, and Trends.Nanomaterials (Basel, Switzerland) · 2020Review
- Impact of Titanium Dioxide Nanoparticles on Cd Phytotoxicity and Bioaccumulation in Rice (International journal of environmental research and public health · 2020Article
- Graphene Oxide-Assisted Promotion of Plant Growth and Stability.Nanomaterials (Basel, Switzerland) · 2020Article
- Effect of Metal Oxide Nanoparticles on the Chemical Speciation of Heavy Metals and Micronutrient Bioavailability in Paddy Soil.International journal of environmental research and public health · 2020Article
- Impact of ZnO nanoparticles on Cd toxicity and bioaccumulation in rice (Oryza sativa L.).Environmental science and pollution research international · 2019Article
- Phytotoxicity of Graphene Family Nanomaterials and Its Mechanisms: A Review.Frontiers in chemistry · 2019Review
- Toxicity of graphene oxide to naked oats (RSC advances · 2018Article
- Detection and Quantification of Graphene-Family Nanomaterials in the Environment.Environmental science & technology · 2018Review
- Carbon Nanomaterials in Agriculture: A Critical Review.Frontiers in plant science · 2016Review
- Penetration and Toxicity of Nanomaterials in Higher Plants.Nanomaterials (Basel, Switzerland) · 2015Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Graphene oxide (GO) is widely used in various fields and is considered to be relatively biocompatible. Herein, "indirect" nanotoxicity is first defined as toxic amplification of toxicants or pollutants by nanomaterials. This work revealed that GO greatly amplifies the phytotoxicity of arsenic (As), a widespread contaminant, in wheat, for example, causing a decrease in biomass and root numbers and increasing oxidative stress, which are thought to be regulated by its metabolisms. Compared with As or GO alone, GO combined with As inhibited the metabolism of carbohydrates, enhanced amino acid and secondary metabolism and disrupted fatty acid metabolism and the urea cycle. GO also triggered damage to cellular structures and electrolyte leakage and enhanced the uptake of GO and As. Co-transport of GO-loading As and transformation of As(V) to high-toxicity As(III) by GO were observed. The generation of dimethylarsinate, produced from the detoxification of inorganic As, was inhibited by GO in plants. GO also regulated phosphate transporter gene expression and arsenate reductase activity to influence the uptake and transformation of As, respectively. Moreover, the above effects of GO were concentration dependent. Given the widespread exposure to As in agriculture, the indirect nanotoxicity of GO should be carefully considered in food safety.
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Registered trials
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