Evidence map›Paper›PMID 25134029›Full record

ArticlePsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2015

Childhood stress exposure among preadolescents with and without family histories of substance use disorders.

Nora E Charles, Stacy R Ryan, Ashley Acheson, Charles W Mathias, Yuanyuan Liang, Donald M Dougherty

Open access · greenAbstract read
In one paragraph

Article in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The age-varying effects of adolescent stress on impulsivity and sensation seeking.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2023
    Article
  4. Article
  5. Article
  6. The Development of Impulsivity and Sensation Seeking: Associations with Substance Use among At-Risk Adolescents.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2020
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nora E CharlesDepartment of Psychiatry.
Stacy R RyanDepartment of Psychiatry.
Ashley AchesonDepartment of Psychiatry.
Charles W MathiasDepartment of Psychiatry.
Yuanyuan LiangDepartment of Epidemiology and Biostatistics.
Donald M DoughertyDepartment of Psychiatry.
The University of Texas Health Science Center at San Antonio · US

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Consequences of Substance Use on the Development of Impulse ControlR01DA026868 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DOUGHERTY, DONALD M · 2010 to 2021
$6.4M
Training in Drug Abuse Research: Behavior and NeurobiologyT32DA031115 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHARLES P FRANCE · 2011 to 2026
$5.2M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthKL2TR001118 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, DOUGHERTY, DONALD M · 2013 to 2017
$3.4M
Relating brain maturation to impulse control and substance use developmentR01DA033997 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ACHESON, ASHLEY, DOUGHERTY, DONALD M · 2012 to 2016
$2.5M
NCATS NIH HHS KL2 TR001118NCATS NIH HHS UL1 TR001120NIDA NIH HHS R01 DA026868NIDA NIH HHS R01-DA026868NIDA NIH HHS R01 DA033997NIDA NIH HHS R01-DA033997NIDA NIH HHS T32 DA031115NIDA NIH HHS T32-DA031115
6 · The paper itself

Abstract

Having a family history of substance use disorders (FH+) increases risk for developing a substance use disorder. This risk may be at least partially mediated by increased exposure to childhood stressors among FH+ individuals. However, measures typically used to assess exposure to stressors are narrow in scope and vary across studies. The nature of stressors that disproportionately affect FH+ children and how these stressors relate to later substance use in this population are not well understood. The purpose of this study was to assess exposure to a broad range of stressors among FH+ and FH- children to better characterize how exposure to childhood stressors relates to increased risk for substance misuse among FH+ individuals. A total of 386 children (305 FH+, 81 FH-; ages 10-12) were assessed using the Stressful Life Events Schedule before the onset of regular substance use. Both the number and severity of stressors were compared. Preliminary follow-up analyses were done for 53 adolescents who subsequently reported initiation of substance use. FH+ children reported more frequent and severe stressors than did FH- children, specifically in the areas of housing, family, school, crime, peers, and finances. Additionally, risk for substance use initiation during early adolescence was influenced directly by having a family history of substance use disorders and also indirectly through increased exposure to stressors among FH+ individuals. In conclusion, FH+ children experience greater stress across multiple domains, which contributes to their risk for substance misuse and related problems during adolescence and young adulthood. (PsycINFO Database Record

Indexed as

Life Change EventsAdolescentChildComorbidityCross-Sectional StudiesFemaleFollow-Up StudiesGene-Environment InteractionGenetic Predisposition to DiseaseHumansMaleMental DisordersRisk FactorsSubstance-Related DisordersTexas

Identifiers

PMID25134029
PMCPMC4484740
OpenAlexW1978325923

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.