ArticleJournal of the mechanical behavior of biomedical materials2014
Adaptive properties of human cementum and cementum dentin junction with age.
Article in Journal of the mechanical behavior of biomedical materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Assessment of transradicular diffusion of different intracanal medicaments through root dentin and cementum: AnJournal of conservative dentistry and endodontics · 2026Article
- Expert consensus on the diagnosis and treatment of cemental tear.International journal of oral science · 2025Review
- Stress Evaluation in Endodontically Treated Virtual Teeth Restored with Composite Fillings and Cast or Fiberglass Posts-A Finite Element Analysis.Biomedicines · 2025Article
- Characterization of craniofacial tissue aging in genetically diverse HET3 male mice with longevity treatment of 17-alpha estradiol.Archives of oral biology · 2025Article
- Atomic force microscopy-mediated mechanobiological profiling of complex human tissues.Biomaterials · 2023Review
- Research progress of biomimetic materials in oral medicine.Journal of biological engineering · 2023Review
- Functional Load Capacity of Teeth with Reduced Periodontal Support: A Finite Element Analysis.Bioengineering (Basel, Switzerland) · 2023Article
- Finite Elements Analysis of Tooth-A Comparative Analysis of Multiple Failure Criteria.International journal of environmental research and public health · 2023Article
- Biomechanical Modelling for Tooth Survival Studies: Mechanical Properties, Loads and Boundary Conditions-A Narrative Review.Materials (Basel, Switzerland) · 2022Review
- Radiographic features in 2D imaging as predictors for justified CBCT examinations of canine-induced root resorption.Dento maxillo facial radiology · 2022Observational
- Forensic determination of dental age by cementum thickness of human teeth.The Journal of forensic odonto-stomatology · 2021Article
- A Computerized Simulation of the Occlusal Surface in Equine Cheek Teeth: A Simplified Model.Frontiers in veterinary science · 2021Article
- Treatment of Pulpectomized Teeth With Trypsin Prior to Transplantation of Mobilized Dental Pulp Stem Cells Enhances Pulp Regeneration in Aged Dogs.Frontiers in bioengineering and biotechnology · 2020Article
- The effect of the surgical microscope on the outcome of root scaling.American journal of translational research · 2020Article
- Biomaterial-Based Approaches for Regeneration of Periodontal Ligament and Cementum Using 3D Platforms.International journal of molecular sciences · 2019Review
- From restoration to regeneration: periodontal aging and opportunities for therapeutic intervention.Periodontology 2000 · 2016Review
- Effect of proteoglycans at interfaces as related to location, architecture, and mechanical cues.Archives of oral biology · 2016Article
- Article
- Calcium orthophosphates (CaPOProgress in biomaterialsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
objectivesThe objective of this study was to evaluate age related changes in physical (structure/mechanical properties) and chemical (elemental/inorganic mineral content) properties of cementum layers interfacing dentin.
methodsHuman mandibular molars (N=43) were collected and sorted by age (younger=19-39, middle=40-60, older=61-81 years). The structures of primary and secondary cementum (PC, SC) types were evaluated using light and atomic force microscopy (AFM) techniques. Chemical composition of cementum layers were characterized through gravimetric analysis by estimating ash weight and concentrations of Ca, Mn, and Zn trace elements in the analytes through inductively coupled plasma mass spectroscopy. The hardness of PC and SC was determined using microindentation and site-specific reduced elastic modulus properties were determined using nanoindentation techniques.
resultsPC contained fibrous 1-3 µm wide hygroscopic radial PDL-inserts. SC illustrated PC-like structure adjacent to a multilayered architecture composing of regions that contained mineral dominant lamellae. The width of the cementum dentin junction (CDJ) decreased as measured from the cementum enamel junction (CEJ) to the tooth apex (49-21 µm), and significantly decreased with age (44-23 µm; p<0.05). The inorganic ratio defined as the ratio of post-burn to pre-burn weight increased with age within primary cementum (PC) and secondary cementum (SC). Cementum showed an increase in hardness with age (PC (0.40-0.46 GPa), SC (0.37-0.43 GPa)), while dentin showed a decreasing trend (coronal dentin (0.70-0.72 GPa); apical dentin (0.63-0.73 GPa)). SIGNIFICANCE: The observed physicochemical changes are indicative of increased mineralization of cementum and CDJ over time. Changes in tissue properties of teeth can alter overall tooth biomechanics and in turn the entire bone-tooth complex including the periodontal ligament. This study provides baseline information about the changes in physicochemical properties of cementum with age, which can be identified as adaptive in nature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.