Evidence map›Paper›PMID 25133510›Full record

SynthesisPloS one2014

Prognostic value of red blood cell distribution width for patients with heart failure: a systematic review and meta-analysis of cohort studies.

Yuan-Lan Huang, Zhi-De Hu, Shi-Jian Liu, Yi Sun, Qin Qin, Bao-Dong Qin, Wei-Wei Zhang, Jian-Rong Zhang, Ren-Qian Zhong, An-Mei Deng

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Red Cell Distribution Width as a Marker of Disease Severity and In-hospital Mortality in Patients with ST-segment Elevation Myocardial Infarction.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuan-Lan HuangDepartment of Laboratory Medicine, NO. 455 Hospital of People's Liberation Army, Shanghai, P. R. China; Department of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China; Department of Laboratory Diagnosis, Changzheng Hospital, Second Military Medical University, Shanghai, P. R. China.
Zhi-De HuDepartment of Laboratory Diagnosis, Changzheng Hospital, Second Military Medical University, Shanghai, P. R. China; Department of Laboratory Medicine, General Hospital of Ji'nan Military Region of People's Liberation Army, Ji'nan, Shandong Province, P. R. China.
Shi-Jian LiuDepartment of Biobank and Biostatistics, Pediatric Translational Institute, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, P. R. China.
Yi SunDepartment of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Qin QinDepartment of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Bao-Dong QinDepartment of Laboratory Diagnosis, Changzheng Hospital, Second Military Medical University, Shanghai, P. R. China.
Wei-Wei ZhangDepartment of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Jian-Rong ZhangDepartment of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.
Ren-Qian ZhongDepartment of Laboratory Diagnosis, Changzheng Hospital, Second Military Medical University, Shanghai, P. R. China.
An-Mei DengDepartment of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University, Shanghai, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMultiple studies have investigated the prognostic role of red blood cell distribution width (RDW) for patients with heart failure (HF), but the results have been inconsistent. The aim of the present study was to estimate the impact of RDW on the prognosis of HF by performing a systematic review and meta-analysis. METHODS AND

resultsThe Embase, PubMed, and Web of Science databases were searched up to November 16, 2013 to identify eligible cohort studies. The quality of each study was assessed using the Newcastle-Ottawa Scale (NOS). The association between RDW, either on admission or at discharge, and HF outcomes (all-cause mortality [ACM], heart transplantation, cardiovascular mortality, and rehospitalization, etc.) were reviewed. The overall hazard ratio (HR) for the effect of RDW on ACM was pooled using a random-effects model, and the publication bias was evaluated using funnel plots and Eggers' tests. Seventeen studies, with a total of 18288 HF patients, were included for systematic review. All eligible studies indicated that RDW on admission and RDW at discharge, as well as its change during treatment, were of prognostic significance for HF patients. The HR for the effect of a 1% increase in baseline RDW on ACM was 1.10 (95% confidence interval: 1.07-1.13), based on pooling of nine studies that provided related data. However, publication bias was observed among these studies.

conclusionsHF patients with higher RDW may have poorer prognosis than those with lower RDW. Further studies are needed to explore the potential mechanisms underlying this association.

Indexed as

Cohort StudiesErythrocyte IndicesErythrocytesHeart FailureHumansPrognosisSensitivity and SpecificitySurvival Analysis

Identifiers

PMID25133510
PMCPMC4136732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.