ArticleJournal of immunology research2014
Activation effects of polysaccharides of Flammulina velutipes mycorrhizae on the T lymphocyte immune function.
Article in Journal of immunology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Safety and efficacy of precision hepatectomy in the treatment of primary liver cancer.BMC surgery · 2023Trial
- Partial replacement of soybean meal with brown mushroom stem powder: Effects on laying performance, egg quality, and serum biochemical indices of lohmann LSL lite hens.Poultry science · 2026Article
- Biological Characterization, Domestication, and the Molecular Basis of Iron Enrichment in a WildJournal of fungi (Basel, Switzerland) · 2026Article
- Oyster mushroom fermentedAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
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- Classification, structure and mechanism of antiviral polysaccharides derived from edible and medicinal fungus.International journal of biological macromolecules · 2021Review
- Dietary fiber in poultry nutrition and their effects on nutrient utilization, performance, gut health, and on the environment: a review.Journal of animal science and biotechnology · 2021Review
- Mulberry leaf polysaccharide supplementation contributes to enhancing the respiratory mucosal barrier immune response in Newcastle disease virus-vaccinated chicks.Poultry science · 2021Article
- Effects ofFrontiers in veterinary science · 2021Article
- Influence of Oyster Mushroom Waste on Growth Performance, Immunity and Intestinal Morphology Compared With Antibiotics in Broiler Chickens.Frontiers in veterinary science · 2020Article
- The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro.BMC complementary and alternative medicine · 2019Article
- Use of Medicinal Mushrooms in Layer Ration.Animals : an open access journal from MDPI · 2019Review
- Immunomodulatory Effects of PhosphorylatedMolecules (Basel, Switzerland) · 2019Article
- Characterization and Antioxidant Activities of Yellow StrainAntioxidants (Basel, Switzerland) · 2019Article
- [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019Article
- Structural elucidation of a polysaccharide from Flammulina velutipes and its immunomodulation activities on mouse B lymphocytes.Scientific reports · 2018Article
- Biodegradation of ramie stalk by Flammulina velutipes: mushroom production and substrate utilization.AMB Express · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flammulina velutipes mycorrhizae have increasingly been produced with increasing of F. velutipes production. A mouse model was thus used to examine potential effect of F. velutipes mycorrhizae on the immune function. Fifty female Wistar mice (5-weeks-old) weighed 15-20 g were randomly allocated into five groups. Polysaccharide of F. velutipes mycorrhizae were treated with mice and mice spleen lymphocytes. The levels of CD3(+), CD4(+), and CD8(+) T lymphocyte, interleukin-2 (IL-2), and tumor necrosis factor-a (TNF-α) were determined. The results showed that the proportions of CD3(+), and CD4(+) T lymphocyte, the ratio of CD4(+)/CD8(+), and the levels of IL-2 and TNF-a were significantly increased in polysaccharide of F. velutipes mycorrhizae, while the proportion of CD8(+) T lymphocyte was decreased in polysaccharide of F. velutipes mycorrhizae-dose dependent manner. Our findings indicated that a long term exposure of polysaccharide of F. velutipes mycorrhizae could activate the T lymphocyte immune function. Polysaccharide of F. velutipes mycorrhizae was expected to develop into the immune health products.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.