Evidence map›Paper›PMID 25133167›Full record

ArticleBioMed research international2014

Serum osteopontin level correlates with carotid-femoral pulse wave velocity in geriatric persons.

Chung-Jen Lee, Ji-Hung Wang, Yu-Chih Chen, Mei-Ling Chen, Chiu-Fen Yang, Bang-Gee Hsu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

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  5. Serum sclerostin as an independent marker of peripheral artery disease in elderly persons.International journal of clinical and experimental pathology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chung-Jen LeeDepartment of Nursing, Tzu Chi College of Technology, Hualien, Taiwan.
Ji-Hung WangDivision of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan ; School of Medicine, Tzu Chi University, Hualien, Taiwan.
Yu-Chih ChenDivision of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Mei-Ling ChenDivision of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Chiu-Fen YangDivision of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Bang-Gee HsuSchool of Medicine, Tzu Chi University, Hualien, Taiwan ; Division of Nephrology, Buddhist Tzu Chi General Hospital, No. 707, Section 3, Chung-Yang Road, Hualien 970, Taiwan.ORCID 0000-0001-9364-4558
Buddhist Tzu Chi General Hospital · TWTzu Chi University · TWTzu Chi College of Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteopontin (OPN) is involved in the regulation of vascular calcification processes. The aim of this study was to evaluate the relationship between fasting serum OPN concentration and carotid-femoral pulse wave velocity (cfPWV) in geriatric persons. Fasting blood samples were obtained from 93 geriatric persons. cfPWV were performed by SphygmoCor system. Serum OPN levels were measured using a commercially available enzyme-linked immunosorbent assay. Geriatric adults who had diabetes (P = 0.007) or dyslipidemia (P = 0.029) had higher cfPWV levels than those without diabetes or dyslipidemia. The univariable linear regression analysis showed that age (P = 0.002), waist circumference (P = 0.048), body mass index (P = 0.004), systolic blood pressure (P = 0.001), diastolic blood pressure (P = 0.036), pulse pressure (P = 0.017), creatinine (P = 0.002), and log-OPN level (P = 0.001) were positively correlated with cfPWV levels, while the high-density lipoprotein cholesterol (HDL-cholesterol) level (P = 0.007) and glomerular filtration rate (P = 0.001) were negatively correlated with cfPWV levels among the geriatric adults. Multivariable forward stepwise linear regression analysis of the significant variables also showed that log-OPN (β = 0.233, R (2) = 0.123, regression coefficient: 1.868, P = 0.011) was still an independent predictor of cfPWV levels in geriatric persons.

Indexed as

Pulse Wave AnalysisAdultAgedCarotid ArteriesFemaleFemoral ArteryHumansLinear ModelsMaleMultivariate AnalysisOsteopontinOsteopontin

Identifiers

PMID25133167
PMCPMC4123499
OpenAlexW2131318612

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.