ArticleJournal of clinical research & bioethics2014
Multimedia Informed Consent Tool for a Low Literacy African Research Population: Development and Pilot-Testing.
Article in Journal of clinical research & bioethics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Providing multimedia information to children and young people increases recruitment to trials: pre-planned meta-analysis of SWATs.BMC medicine · 2023Pooled it
- A randomized study of multimedia informational aids for research on medical practices: Implications for informed consent.Clinical trials (London, England) · 2017Trial
- A multimedia consent tool for research participants in the Gambia: a randomized controlled trial.Bulletin of the World Health Organization · 2015Trial
- Development of a multimedia informed consent tool for fixed prosthodontic treatment: A cognitive theory-based approach to enhance patient understanding.PEC innovation · 2026Article
- Biobank consent preferences and implications for a mixed consent model: biomedical researchers vs. community stakeholders in a semi-urban Yoruba community, Nigeria.Frontiers in genetics · 2026Article
- Review
- Guidelines for the Creation of Accessible Consent Materials and Procedures: Lessons from Research with Autistic People and People with Intellectual Disability.Autism in adulthood · 2025Article
- Developing guidelines for culturally relevant informed consent: an example from Lebanon.PLOS mental health · 2025Article
- Researchers experience and views on participants' comprehension of informed consent in clinical trials in Malawi: a descriptive qualitative study.BMC medical ethics · 2024Article
- Informed proxy consent for ancient DNA research.Communications biology · 2024Article
- Beyond translations, perspectives for researchers to consider to enhance comprehension during consent processes for health research in sub-saharan Africa: a scoping review.BMC medical ethics · 2023Article
- Developing a Digital Medication Adherence Intervention for and With Patients With Asthma and Low Health Literacy: Protocol for a Participatory Design Approach.JMIR formative research · 2023Article
- Recruitmentology and the politics of consent in clinical research.Lancet (London, England) · 2023Article
- Informed consent for controlled human infection studies in low- and middle-income countries: Ethical challenges and proposed solutions.Bioethics · 2020Article
- Digital tools for the recruitment and retention of participants in randomised controlled trials: a systematic map.Trials · 2020Review
- Challenges arising when seeking broad consent for health research data sharing: a qualitative study of perspectives in Thailand.BMC medical ethics · 2018Article
- Moving Forward on Consent Practices in Australia.Journal of bioethical inquiry · 2018Article
- Recall and decay of consent information among parents of infants participating in a randomized controlled clinical trial using an audio-visual tool in The Gambia.Human vaccines & immunotherapeutics · 2017Article
- Postal recruitment and consent obtainment from index cases of narcolepsy.BMC medical ethics · 2016Article
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundInternational guidelines recommend the use of appropriate informed consent procedures in low literacy research settings because written information is not known to guarantee comprehension of study information.
objectivesThis study developed and evaluated a multimedia informed consent tool for people with low literacy in an area where a malaria treatment trial was being planned in The Gambia.
methodsWe developed the informed consent document of the malaria treatment trial into a multimedia tool integrating video, animations and audio narrations in three major Gambian languages. Acceptability and ease of use of the multimedia tool were assessed using quantitative and qualitative methods. In two separate visits, the participants' comprehension of the study information was measured by using a validated digitised audio questionnaire.
resultsThe majority of participants (70%) reported that the multimedia tool was clear and easy to understand. Participants had high scores on the domains of adverse events/risk, voluntary participation, study procedures while lowest scores were recorded on the question items on randomisation. The differences in mean scores for participants' 'recall' and 'understanding' between first and second visits were statistically significant (F (1,41)=25.38, p<0.00001 and (F (1, 41) = 31.61, p<0.00001 respectively.
conclusionsOur locally developed multimedia tool was acceptable and easy to administer among low literacy participants in The Gambia. It also proved to be effective in delivering and sustaining comprehension of study information across a diverse group of participants. Additional research is needed to compare the tool to the traditional consent interview, both in The Gambia and in other sub-Saharan settings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.