ReviewWorld journal of gastrointestinal pharmacology and therapeutics2014
Visceral hypersensitivity and electromechanical dysfunction as therapeutic targets in pediatric functional dyspepsia.
Review in World journal of gastrointestinal pharmacology and therapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- P INK1/PARKIN mitophagy: a potential regulator of mitochondrial homeostasis in functional dyspepsia.Frontiers in physiology · 2026Pooled it
- Effect of Sihogyeji-tang on functional dyspepsia: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Percutaneous Electrical Nerve Field Stimulation in Children and Adolescents With Functional Dyspepsia-Integrating a Behavioral Intervention.Neuromodulation : journal of the International Neuromodulation Society · 2024Article
- Association of vitamin D and functional dyspepsia: a case-control study.Annals of medicine and surgery (2012) · 2023Article
- Editorial: Insights into structural and functional organization of the brain: evidence from neuroimaging and non-invasive brain stimulation techniques.Frontiers in psychiatry · 2023Article
- An Update on the Assessment and Management of Pediatric Abdominal Pain.Pediatric health, medicine and therapeutics · 2021Review
- Rumination Syndrome in Children and Adolescents: A Mini Review.Frontiers in pediatrics · 2021Review
- Choosing an Animal Model for the Study of Functional Dyspepsia.Canadian journal of gastroenterology & hepatology · 2018Review
- Enhanced sympathetic nerve activity induced by neonatal colon inflammation induces gastric hypersensitivity and anxiety-like behavior in adult rats.American journal of physiology. Gastrointestinal and liver physiology · 2016Article
- Functional Nausea in Children: A Review of the Literature and Need for Diagnostic Criteria.Children (Basel, Switzerland) · 2016Review
- Therapeutic effect of melatonin on pediatric functional dyspepsia: A pilot study.World journal of gastrointestinal pharmacology and therapeutics · 2016Article
- Noninflammatory upregulation of nerve growth factor underlies gastric hypersensitivity induced by neonatal colon inflammation.American journal of physiology. Regulatory, integrative and comparative physiology · 2016Article
- Present state and future challenges in pediatric abdominal pain therapeutics research: Looking beyond the forest.World journal of gastrointestinal pharmacology and therapeutics · 2015Article
- Perspectives on the clinical significance of functional pain syndromes in children.Journal of pain research · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Functional gastrointestinal disorders (FGID) are common clinical syndromes diagnosed in the absence of biochemical, structural, or metabolic abnormalities. They account for significant morbidity and health care expenditures and are identifiable across variable age, geography, and culture. Etiology of abdominal pain associated FGIDs, including functional dyspepsia (FD), remains incompletely understood, but growing evidence implicates the importance of visceral hypersensitivity and electromechanical dysfunction. This manuscript explores data supporting the role of visceral hypersensitivity and electromechanical dysfunction in FD, with focus on pediatric data when available, and provides a summary of potential therapeutic targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.