ReviewWorld journal of gastrointestinal pathophysiology2014
Multidisciplinary and evidence-based management of fistulizing perianal Crohn's disease.
Review in World journal of gastrointestinal pathophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Perianal fistulizing Crohn's disease: Clinical practice update from Colitis and Crohn's Foundation (India).Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Guideline
- Treatment of perianal abscess and anal fistula in infants: a systematic review.Frontiers in surgery · 2025Pooled it
- Identifying landmark factors of anal fistulas through predictive modelling for adverse surgical outcomes: a retrospective cohort study.BMC surgery · 2025Article
- How to Approach the Difficult Perineum in Crohn's Disease.Clinics in colon and rectal surgery · 2025Review
- Navigating the complexities of perianal Crohn's disease: Diagnostic strategies, treatment approaches, and future perspectives.World journal of gastroenterology · 2024Article
- Crohn's Disease-Associated and Cryptoglandular Fistulas: Differences and Similarities.Journal of clinical medicine · 2023Review
- The relationship between perianal fistula activity and abdominal adipose tissue in Crohn's disease: an observational study.Insights into imaging · 2022Article
- Perianal magnetic resonance imaging findings and their potential impact on outcome in children with perianal fistulizing Crohn disease.Pediatric radiology · 2021Article
- Management of perianal fistula in inflammatory bowel disease: identification of prognostic factors associated with surgery.Langenbeck's archives of surgery · 2021Article
- Treatment Strategy for Perianal Fistulas in Crohn Disease Patients: The Surgeon's Point of View.Annals of coloproctology · 2021Review
- Diagnostic accuracy of faecal calprotectin in patients with active perianal fistulas.United European gastroenterology journal · 2019Observational
- Management of anoperineal lesions in Crohn's disease: a French National Society of Coloproctology national consensus.Techniques in coloproctology · 2018Review
- Surgical management of complicated rectovaginal fistulas and the role of omentoplasty.Techniques in coloproctology · 2017Article
- A new method for evaluation of perianal fistula: digital infrared thermal imaging.Techniques in coloproctology · 2016Article
- Indian Society of Gastroenterology consensus statements on Crohn's disease in India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2015Article
- Medical and surgical management of perianal Crohn's disease.Annals of gastroenterologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Perianal symptoms are common in patients with Crohn's disease and cause considerable morbidity. The etiology of these symptoms include skin tags, ulcers, fissures, abscesses, fistulas or stenoses. Fistula is the most common perianal manifestation. Multiple treatment options exist although very few are evidence-based. The phases of treatment include: drainage of infection, assessment of Crohn's disease status and fistula tracts, medical therapy, and selective operative management. The impact of biological therapy on perianal Crohn's disease is uncertain given that outcomes are conflicting. Operative treatment to eradicate the fistula tract can be attempted once infection has resolved and Crohn's disease activity is controlled. The operative approach should be tailored according to the anatomy of the fistula tract. Definitive treatment is challenging with medical and operative treatment rarely leading to true healing with frequent complications and recurrence. Treatment success must be weighed against the risk of complications, specially anal sphincter injury. A full understanding of the etiology and all potential therapeutic options is critical for success. Multidisciplinary management of fistulizing perianal Crohn's disease is crucial to improve outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.