Evidence map›Paper›PMID 25132774›Full record

ArticleWorld journal of gastroenterology2014

Risk factors associated with early and late HAT after adult liver transplantation.

Yi Yang, Ji-Chun Zhao, Lu-Nan Yan, Yu-Kui Ma, Bin Huang, Ding Yuan, Bo Li, Tian-Fu Wen, Wen-Tao Wang, Ming-Qing Xu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Meta-analysis and meta-regression of outcomes for adult living donor liver transplantation versus deceased donor liver transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
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  10. Donor diabetes mellitus is a risk factor for diminished outcome after liver transplantation: a nationwide retrospective cohort study.Transplant international : official journal of the European Society for Organ Transplantation · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yi YangYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Ji-Chun ZhaoYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Lu-Nan YanYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Yu-Kui MaYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Bin HuangYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Ding YuanYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Bo LiYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Tian-Fu WenYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Wen-Tao WangYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Ming-Qing XuYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Jia-Yin YangYi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo identify risk factors that might contribute to hepatic artery thrombosis (HAT) after liver transplantation (LT).

methodsThe perioperative and follow-up data of a total of 744 liver transplants, performed from February 1999 to July 2010, were retrospectively reviewed. HAT developed in 20 patients (2.7%). HAT was classified as early (occurring in fewer than 30 d post LT) or late (occurring more than 30 d post LT). Early HAT developed in 14 patients (1.9%). Late HAT developed in 6 patients (0.8%). Risk factors associated with HAT were analysed using the χ(2) test for univariate analysis and logistic regression for multivariate analysis.

resultsLack of ABO compatibility, recipient/donor weight ratio ≥ 1.15, complex arterial reconstruction, duration time of hepatic artery anastomosis > 80 min, duration time of operation > 10 h, dual grafts, number of units of blood received intraoperatively ≥ 7, number of units of fresh frozen plasma (FFP) received intraoperatively ≥ 6, postoperative blood transfusion and postoperative FFP use were significantly associated with early HAT in the univariate analysis (P < 0.1). After logistic regression, independent risk factors associated with early HAT were recipient/donor weight ratio ≥ 1.15 (OR = 4.499), duration of hepatic artery anastomosis > 80 min (OR = 5.429), number of units of blood received intraoperatively ≥ 7 (OR = 4.059) and postoperative blood transfusion (OR = 6.898). Graft type (whole/living-donor/split), duration of operation > 10 h, retransplantation, rejection reaction, recipients with diabetes preoperatively and recipients with a high level of blood glucose or diabetes postoperatively were significantly associated with late HAT in the univariate analysis (P < 0.1). After logistic regression, the independent risk factors associated with early HAT were duration of operation > 10 h (OR = 6.394), retransplantation (OR = 21.793) and rejection reactions (OR = 16.936).

conclusionEarly detection of these risk factors, strict surveillance protocols by Doppler ultrasound and prophylactic anticoagulation for recipients at risk might be determined prospectively.

Indexed as

Hepatic ArteryAdolescentAdultAgedArterial Occlusive DiseasesChi-Square DistributionFemaleHumansLiver TransplantationLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPredictive Value of TestsRetrospective StudiesBlood transfusionComplicationHepatic artery thrombosisLiver transplantationRisk factors

Identifiers

PMID25132774
PMCPMC4130865
OpenAlexW1985684078

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.