Evidence map›Paper›PMID 25132746›Full record

ReviewWorld journal of gastroenterology2014

Prognostic relevance of minimal residual disease in colorectal cancer.

Ulrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Colorectal cancer and dormant metastases: Put to sleep or destroy?World journal of gastrointestinal oncology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ulrich BorkUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Robert GrützmannUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Nuh N RahbariUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Sebastian SchölchUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Marius DistlerUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Christoph ReissfelderUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Moritz KochUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Jürgen WeitzUlrich Bork, Robert Grützmann, Nuh N Rahbari, Sebastian Schölch, Marius Distler, Christoph Reissfelder, Moritz Koch, Jürgen Weitz, Department of GI, Thoracic and Vascular Surgery, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany.
Technische Universität Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presence of occult minimal residual disease in patients with colorectal cancer (CRC) has a strong prognostic impact on survival. Minimal residual disease plays a major role in disease relapse and formation of metastases in CRC. Analysis of circulating tumor cells (CTC) in the blood is increasingly used in clinical practice for disease monitoring of CRC patients. In this review article the role of CTC, disseminated tumor cells (DTC) in the bone marrow and micrometastases and isolated tumor cells (ITC) in the lymph nodes will be discussed, including literature published until September 2013. Occult disease is a strong prognostic marker for patient survival in CRC and defined by the presence of CTC in the blood, DTC in the bone marrow and/or micrometastases and ITC in the lymph nodes. Minimal residual disease could be used in the future to identify patient groups at risk, who might benefit from individualized treatment options.

Indexed as

AnimalsBone MarrowColorectal NeoplasmsHumansLymphatic MetastasisLymph NodesNeoplasm MicrometastasisNeoplasm Recurrence, LocalNeoplasm, ResidualNeoplastic Cells, CirculatingPrecision MedicinePredictive Value of TestsRisk AssessmentRisk FactorsTreatment OutcomeCirculating tumor cellsColorectal cancerDisseminated tumor cellsIsolated tumor cellsMicrometastasesMinimal residual diseaseOccult disease

Identifiers

PMID25132746
PMCPMC4130837
OpenAlexW1993343562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.