ReviewCellular & molecular immunology2014
Adrenomedullin and endocrine control of immune cells during pregnancy.
Review in Cellular & molecular immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- AHR activated placental adrenomedullin: A plausible factor in smoke-induced preeclampsia protection.Placenta · 2025Article
- Adrenomedullin improved endothelial dysfunction via receptor-Akt pathway in rats with obesity-related hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Article
- Animal models of the placenta accreta spectrum: current status and further perspectives.Frontiers in endocrinology · 2023Review
- Maternal Low Volume Circulation Relates to Normotensive and Preeclamptic Fetal Growth Restriction.Frontiers in medicine · 2022Review
- Preeclampsia Is a Syndrome with a Cascade of Pathophysiologic Events.Journal of clinical medicine · 2020Review
- Deletion of atypical chemokine receptor 3 (ACKR3) increases immune cells at the fetal-maternal interface.Placenta · 2020Article
- Higher adrenomedullin levels during implantation are associated with successful pregnancy.Future science OA · 2020Article
- Emerging roles of atypical chemokine receptor 3 (ACKR3) in normal development and physiology.Cytokine · 2018Review
- Elevated levels of adrenomedullin in eutopic endometrium and plasma from women with endometriosis.Fertility and sterility · 2018Article
- Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium.Biology of reproduction · 2017Article
- Hyperoxia exposure disrupts adrenomedullin signaling in newborn mice: Implications for lung development in premature infants.Biochemical and biophysical research communications · 2017Article
- Reproductive immunology issue 2: cellular and molecular biology.Cellular & molecular immunology · 2014Article
- Reproductive immunology issue one: cellular and molecular biology.Cellular & molecular immunology · 2014Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The immunology of pregnancy is complex and incompletely understood. Aberrant immune activity in the decidua and in the placenta is believed to play a role in diseases of pregnancy, such as infertility, miscarriage, fetal growth restriction and preeclampsia. Here, we briefly review the endocrine control of uterine natural killer cell populations and their functions by the peptide hormone adrenomedullin. Studies in genetic animal models have revealed the critical importance of adrenomedullin dosage at the maternal-fetal interface, with cells from both the maternal and fetal compartments contributing to essential aspects underlying appropriate uterine receptivity, implantation and vascular remodeling of spiral arteries. These basic insights into the crosstalk between the endocrine and immune systems within the maternal-fetal interface may ultimately translate to a better understanding of the functions and consequences of dysregulated adrenomedullin levels in clinically complicated pregnancies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.