Evidence map›Paper›PMID 25131156›Full record

ArticleHealth services research2015

Impact of a pharmacy benefit change on new use of mail order pharmacy among diabetes patients: the Diabetes Study of Northern California (DISTANCE).

Andrew J Karter, Melissa M Parker, O Kenrik Duru, Dean Schillinger, Nancy E Adler, Howard H Moffet, Alyce S Adams, James Chan, Willam H Herman, Julie A Schmittdiel

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Health services research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02621476 (Encouraging Mail Order Pharmacy Use to Improve Outcomes and Reduce Disparities), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02621476 nacompletednot on this mapstarted 2017, after this paper: background citation

Encouraging Mail Order Pharmacy Use to Improve Outcomes and Reduce Disparities

TypeinterventionalSponsorKaiser PermanenteRan2017 to 2022Enrolled63,012ConditionsDiabetes MellitusArmsStandardized intervention, Usual care
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. The effect of mail order pharmacy outreach on older patients with diabetes.Journal of the American Geriatrics Society · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Andrew J KarterDivision of Research, Kaiser Permanente Northern California, Oakland, CA.
Melissa M Parker
O Kenrik Duru
Dean Schillinger
Nancy E Adler
Howard H Moffet
Alyce S Adams
James Chan
Willam H Herman
Julie A Schmittdiel
Kaiser Permanente · USSan Francisco General Hospital · USUniversity of California, San Francisco · USUniversity of California System · USUniversity of Michigan–Ann Arbor · US

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAISSE, CHRISTIAN · 2003 to 2019
$21.8M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Ethnic Disparities in Diabetes ComplicationsR01DK065664 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2004 to 2008
$3.3M
Diabetes and Aging in a Multi-Ethnic PopulationR01DK081796 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI HUANG, ELBERT S., KARTER, ANDREW JOHN · 2009 to 2013
$2.9M
Learnings in Diabetes Prevention from an Integrated Delivery SystemU58DP002721 · DP · KAISER FOUNDATION RESEARCH INSTITUTE · PI SCHMITTDIEL, JULIE A · 2010 to 2014
$2.5M
Educational Disparities in Diabetes ComplicationsR01HD046113 · NICHD · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2003 to 2006
$1.6M
Impact of Medicare Part D on Cancer and Diabetes Disparities among Dual EnrolleesR01AG032249 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI ADAMS, ALYCE SOPHIA · 2009 to 2011
$1.5M
Medication Adherence and Social Disparities in DiabetesR01DK080726 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2009 to 2012
$1.5M
Failure to Utilize Diabetes Health Services Following a ReferralRC1DK086178 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2009 to 2010
$497k
Translating Research Into Action for Diabetes (TRIAD) Legacy StudyU58DP002641 · DP · KAISER FOUNDATION RESEARCH INSTITUTE · PI KARTER, ANDREW JOHN · 2010 to 2012
$259k
NCCDPHP CDC HHS U58 DP002641NCCDPHP CDC HHS U58 DP002721NIA NIH HHS R01 AG032249NICHD NIH HHS R01 HD046113NIDDK NIH HHS P30 DK063720NIDDK NIH HHS P30 DK092924NIDDK NIH HHS R01 DK065664NIDDK NIH HHS R01 DK080726NIDDK NIH HHS R01DK080726NIDDK NIH HHS R01 DK081796NIDDK NIH HHS R01DK081796NIDDK NIH HHS R01DK65664NIDDK NIH HHS RC1 DK086178
6 · The paper itself

Abstract

objectiveTo assess the impact of a pharmacy benefit change on mail order pharmacy (MOP) uptake. DATA SOURCES/STUDY

settingRace-stratified, random sample of diabetes patients in an integrated health care delivery system. STUDY

designIn this natural experiment, we studied the impact of a pharmacy benefit change that conditionally discounted medications if patients used MOP and prepaid two copayments. We compared MOP uptake among those exposed to the benefit change (n = 2,442) and the reference group with no benefit change (n = 8,148), and estimated differential MOP uptake across social strata using a difference-in-differences framework. DATA COLLECTION/EXTRACTION

methodsAscertained MOP uptake (initiation among previous nonusers). PRINCIPAL

findingsThirty percent of patients started using MOP after receiving the benefit change versus 9 percent uptake among the reference group (p < .0001). After adjustment, there was a 26 percentage point greater MOP uptake (benefit change effect). This benefit change effect was significantly smaller among patients with inadequate health literacy (15 percent less), limited English proficiency (14 percent less), and among Latinos and Asians (24 and 16 percent less compared to Caucasians).

conclusionsConditionally discounting medications delivered by MOP effectively stimulated MOP uptake overall, but it unintentionally widened previously existing social gaps in MOP use because it stimulated less MOP uptake in vulnerable populations.

Indexed as

Postal ServiceAgedCaliforniaDeductibles and CoinsuranceDiabetes MellitusFemaleHumansHypoglycemic AgentsInsurance, Pharmaceutical ServicesMaleMiddle AgedPharmaceutical ServicesSocioeconomic FactorsHypoglycemic Agentscomparative effectivenessdifference-in-differenceshealth disparitiesinverse probability treatment weightingMail order pharmacymarginal structural modelpharmacy benefit designs

Identifiers

PMID25131156
PMCPMC4329275
OpenAlexW2148132210

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.