ReviewThe Journal of allergy and clinical immunology2014
Stress and asthma: novel insights on genetic, epigenetic, and immunologic mechanisms.
Review in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 2 syntheses or guidelines pooled it, 181 citations in OpenAlex.
- The Impact of War on Asthma, a Systematic Review and Meta-Analysis: An EAACI Task Force Report.Allergy · 2026Pooled it
- Exposure to violence, chronic stress, nasal DNA methylation, and atopic asthma in children.Pediatric pulmonology · 2021Pooled it
- Violence-related distress and lung function in two longitudinal studies of youth.The European respiratory journal · 2022Trial
- Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation.Scientific reports · 2016Trial
- Impact of Chronic Stress and Trauma on Asthma Pathophysiology and Outcomes.Current allergy and asthma reports · 2026Review
- Current perspectives on the psychological stress-immune axis in asthma: Pathophysiology, interventions, and significance for patient care.The World Allergy Organization journal · 2026Review
- Hereditary angioedema and post traumatic stress disorder: a reciprocal relationship?Orphanet journal of rare diseases · 2026Article
- How the Asthmatic Patients Handle During War?Immunity, inflammation and disease · 2026Observational
- Exploring the causal link between childhood maltreatment and asthma: a Mendelian randomization study.European journal of psychotraumatology · 2025Article
- Dispensing of medicines for asthma and chronic obstructive pulmonary disease through the government health insurance in Syria: a retrospective analysis.Global health action · 2025Article
- Asthma: Biomedical and Psychobiological Perspectives.Biopsychosocial science and medicine · 2025Review
- Life Stressors, Resilience Resources, and Asthma Among Adults in the Hispanic Community Health Study/Study of Latinos.The journal of allergy and clinical immunology. In practice · 2025Article
- Work Stressors and Asthma in Female and Male US Workers: Findings From the National Health Interview Survey.American journal of industrial medicine · 2025Article
- Sociocultural Stressors and Asthma among Adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).Annals of the American Thoracic Society · 2025Article
- Neuroimmune Circuits in Allergic Diseases.Annual review of immunology · 2025Review
- Review
- Creating home-based pulmonary rehabilitation programs for patients with asthma: insights from practice.Journal of Yeungnam medical science · 2025Article
- The effects of violence and related stress on asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Review
- Recommendations for Clinicians to Combat Environmental Disparities in Pediatric Asthma: A Review.Chest · 2024Review
- Sleep, brain systems, and persistent stress in early adolescents during COVID-19: Insights from the ABCD study.Journal of affective disorders · 2024Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In the United States the economically disadvantaged and some ethnic minorities are often exposed to chronic psychosocial stressors and disproportionately affected by asthma. Current evidence suggests a causal association between chronic psychosocial stress and asthma or asthma morbidity. Recent findings suggest potential mechanisms underlying this association, including changes in the methylation and expression of genes that regulate behavioral, autonomic, neuroendocrine, and immunologic responses to stress. There is also evidence suggesting the existence of susceptibility genes that predispose chronically stressed youth to both post-traumatic stress disorder and asthma. In this review we critically examine published evidence and suggest future directions for research in this field.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.