ArticleTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2014
Relationship between IL-10 expression and prognosis in patients with primary breast cancer.
Article in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Benefits in radical mastectomy protocol: a randomized trial evaluating the use of regional anesthesia.Scientific reports · 2018Trial
- Breast cancer immunotherapy: mechanisms of immune evasion, biomarkers, and emerging therapeutic strategies.Molecular cancer · 2026Review
- Association of Elevated Expression Levels ofJournal of personalized medicine · 2022Article
- Studying the Effect of Garlic Consumption and Endurance Training on Serum Levels of Some Pro-and Anti-inflammatory Cytokines in Female Mice with Breast Cancer - A Randomized Trial.International journal of preventive medicine · 2022Article
- Intermittent hypoxia induces tumor immune escape in murine S180 solid tumors via the upregulation of TGF-βSleep & breathing = Schlaf & Atmung · 2021Article
- Breast cancer therapy affects the expression of antineonatal Nav1.5 antibodies in the serum of patients with breast cancer.Oncology letters · 2021Article
- A Survey on the Role of Interleukin-10 in Breast Cancer: A Narrative.Reports of biochemistry & molecular biology · 2018Article
- Diagnostic value of PD-1 mRNA expression combined with breast ultrasound in breast cancer patients.Therapeutics and clinical risk management · 2018Article
- A panel containing PD-1, IL-2Rα, IL-10, and CA15-3 as a biomarker to discriminate breast cancer from benign breast disease.Cancer management and research · 2018Article
- Interleukin-10: A double-edged sword in breast cancer.Tzu chi medical journalReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This retrospective study was designed to investigate the relationship between the expression of IL-10, CD4, CD8, and FOXP3 and clinicopathological features and prognosis in breast cancer patients. The expression of IL-10, CD4, CD8, and FOXP3 was detected by immunohistochemistry. Staining intensity of only IL-10 was associated with disease-free survival and distance disease-free survival (P<0.05). Staining density of IL-10 in stromal cells was associated with overall survival and distance disease-free survival (P<0.05). IL-10 expression levels might be used as a prognostic indicator for the recurrence, metastasis, and survival of breast cancer patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.