Evidence map›Paper›PMID 25129406›Full record

Observational studyJournal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

A Trimodality Comparison of Volumetric Bone Imaging Technologies. Part II: 1-Yr Change, Long-Term Precision, and Least Significant Change.

Andy K O Wong, Karen A Beattie, Kevin K H Min, Zamir Merali, Colin E Webber, Christopher L Gordon, Alexandra Papaioannou, Angela M W Cheung, Jonathan D Adachi

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effects of a 20-week high-intensity strength and sprint training program on tibial bone structure and strength in middle-aged and older male sprint athletes: a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andy K O WongDepartment of Medicine, McMaster University, Hamilton, ON, Canada. Electronic address: wongko@mcmaster.ca.
Karen A BeattieDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Kevin K H MinHealth Sciences, McMaster University, Hamilton, ON, Canada.
Zamir MeraliDepartment of Medicine, University Health Network, Toronto, ON, Canada.
Colin E WebberDepartment of Nuclear Medicine, Hamilton Health Sciences, Hamilton, ON, Canada.
Christopher L GordonDepartment of Nuclear Medicine, McMaster University, Hamilton, ON, Canada.
Alexandra PapaioannouDivision of Geriatrics, Hamilton Health Sciences, Hamilton, ON, Canada.
Angela M W CheungOsteoporosis Program, University Health Network, Toronto, ON, Canada.
Jonathan D AdachiDepartment of Medicine, McMaster University, Hamilton, ON, Canada.

Funding

CIHR 88225-1
6 · The paper itself

Abstract

The previous article in this 3-part series demonstrated short-term precision and validity for volumetric bone outcome quantification using in vivo peripheral (p) quantitative computed tomography (pQCT) and magnetic resonance imaging (MRI) modalities at resolutions 200 μm or higher. However, 1-yr precision error and clinically significant references are yet to be reported for these modalities. This study examined 59 women with mean age of 75 ± 9 yr and body mass index of 26.84 ± 4.77 kg/m², demonstrating the lowest 1-yr precision error, standard errors of the estimate, and least significant change values for high-resolution (hr) pQCT followed by pQCT, and 1.0-T pMRI for all volumetric bone outcomes except trabecular number. Like short-term precision, 1-yr statistics for trabecular separation were similar across modalities. Excluding individuals with a previous history of fragility fractures, or who were current users of antiresorptives reduced 1-yr change for bone outcomes derived from pQCT and pMR images, but not hr-pQCT images. In Part II of this 3-part series focused on trimodality comparisons of 1-yr changes, hr-pQCT was recommended to be the prime candidate for quantifying change where smaller effect sizes are expected, but pQCT was identified as a feasible alternative for studies expecting larger changes.

Indexed as

Magnetic Resonance ImagingTomography, X-Ray ComputedAgedAged, 80 and overBone and BonesCohort StudiesFemaleHumansLongitudinal StudiesMiddle AgedOrgan SizeOsteoporosis, PostmenopausalReproducibility of Resultsleast significant changelong-term precisionMRIpQCTsegmentationstandard error of the estimate

Identifiers

PMID25129406
PMCPMC5092156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.