Evidence map›Paper›PMID 25129318›Full record

ReviewThe Journal of infection2014

Neonatal candidiasis: diagnosis, prevention, and treatment.

Rachel G Greenberg, Daniel K Benjamin

Abstract readReview
In one paragraph

Review in The Journal of infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Fluconazole prophylaxis in preterm infants: a systematic review.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Infection prevention and control ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Changes in the epidemiology of neonatal bacteremia during the COVID-19 pandemic in Wuhan, China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  10. Review
  11. Neonatal Sepsis: A Comprehensive Review.Antibiotics (Basel, Switzerland) · 2024
    Review
  12. Congenital Sepsis withMicroorganisms · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Antibodies targetingFrontiers in immunology · 2022
    Article
  19. Article
  20. Journal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rachel G GreenbergDuke University Medical Center, 2424 Erwin Road, Suite 504, Durham, NC 27705, USA. Electronic address: rachel.greenberg@duke.edu.
Daniel K BenjaminDuke Clinical Research Institute, Duke University Medical Center, P.O. Box 17969, Durham, NC 27715, USA. Electronic address: danny.benjamin@duke.edu.
Clinical Research Institute · USDuke University Hospital · US

Funding

Prevention of Invasive Candidiasis: PK, Safety, and Neurodevelopmental OutcomesR01HD057956 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2008 to 2012
$2.8M
Mentorship of early-career pediatricians in quantitiative methods and therapeuticK24HD058735 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2009 to 2018
$1.5M
NICHD NIH HHS HHSN275201000003INICHD NIH HHS K24 HD058735NICHD NIH HHS R01 HD057956
6 · The paper itself

Abstract

Infection with Candida species is associated with significant morbidity and mortality in infants. The incidence of Candida infection varies widely across centers, likely due to differences in practice related to modifiable risk factors such as exposure to empiric antibiotics and length of parenteral nutrition. Early diagnosis of Candida and prompt treatment with appropriate antifungal agents, such as fluconazole, amphotericin B deoxycholate, and micafungin, are critical for improved outcomes. This paper reviews the current literature relating to the prevention, diagnosis, and treatment of Candida infections in the neonatal intensive care unit.

Indexed as

Age FactorsCandidiasisHumansInfant, NewbornIntensive Care Units, NeonatalAntifungal therapyCandidaDiagnosisNeonatal intensive care unitPrevention

Identifiers

PMID25129318
PMCPMC4252884
OpenAlexW2010042214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.