Evidence map›Paper›PMID 25128608›Full record

Observational studyJournal of pain and symptom management2015

Comparison of seven-day and repeated 24-hour recall of symptoms in the first 100 days after hematopoietic cell transplantation.

William A Wood, Allison M Deal, Antonia V Bennett, Sandra A Mitchell, Amy P Abernethy, Ethan Basch, Charlotte Bailey, Bryce B Reeve

Registry-linked trialAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Journal of pain and symptom management, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02564458 (Fitness in Allogeneic Stem Cell Transplantation), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02564458 nacompletednot on this map

Fitness in Allogeneic Stem Cell Transplantation

TypeinterventionalSponsorUNC Lineberger Comprehensive Cancer CenterRan2015 to 2018Enrolled35ConditionsHematopoietic Stem Cell TransplantationArmsInterval Exercise Training/Motivational Accelerometry
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

William A WoodLineberger Comprehensive Cancer Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. Electronic address: wawood@med.unc.edu.
Allison M DealBiostatistics Core Facility, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Antonia V BennettLineberger Comprehensive Cancer Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Sandra A MitchellOutcomes Research Branch, Division of Cancer Control and Population Science, National Cancer Institute, Bethesda, Maryland, USA.
Amy P AbernethyDivision of Medical Oncology, Duke University Medical Center, Duke Cancer Institute, Durham, North Carolina, USA.
Ethan BaschLineberger Comprehensive Cancer Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Charlotte BaileyLineberger Comprehensive Cancer Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Bryce B ReeveLineberger Comprehensive Cancer Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

North Carolina Translational & Clinical Sciences Institute (NC TraCS)KL2TR001109 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$5.7M
UNC Clinical Translation Science Award-K12 Scholars Program (KL2)KL2TR000084 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2012 to 2013
$2.3M
NCATS NIH HHS KL2 TR000084NCATS NIH HHS KL2TR000084NCATS NIH HHS KL2 TR001109
6 · The paper itself

Abstract

contextPatient-reported outcomes (PROs) provide a way to understand the effects of hematopoietic cell transplantation (HCT)-related stress on patients' lives. We previously reported that weekly collection of PROs is feasible.

objectivesHere, we report on the feasibility of daily patient-reported symptom collection and examine the relationship between daily vs. weekly symptom reporting over time.

methodsWe analyzed data from 32 autologous and allogeneic HCT patients obtained until Day (D) +100. We used questions from the PRO version of the Common Terminology Criteria for Adverse Events to capture symptoms.

resultsWe found that overall rates of daily survey completion were moderate to high (range 67%-86%). The effect size of the difference between the maximum daily severity score and the weekly severity score ranged from 0.15 to 0.35, and the concordance correlation coefficient ranged from 0.513 to 0.834. Concordance of daily and weekly surveys was higher for maximum daily severity rating and mean daily severity rating than for minimum daily severity rating or most recent daily severity rating.

conclusionWe conclude that a seven-day recall period for symptom severity provides acceptable accuracy and precision in the first 100 days after HCT. Further studies to explore the utility of daily symptom reporting within specific clinical contexts may be warranted.

Indexed as

Medical RecordsCohort StudiesFeasibility StudiesHematopoietic Stem Cell TransplantationHumansMiddle AgedPilot ProjectsSelf ReportSurveys and QuestionnairesTime FactorsHematopoietic stem cell transplantationpatient-reported outcomesPRO-CTCAEsymptom burden

Identifiers

PMID25128608
PMCPMC4326621

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.