ArticleLangenbeck's archives of surgery2015
Management of the open abdomen using vacuum-assisted wound closure and mesh-mediated fascial traction.
Article in Langenbeck's archives of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- [Clinical disaster medicine: recommendations of the Surgical Working Group for Military and Emergency Surgery].Unfallchirurgie (Heidelberg, Germany) · 2025Guideline
- Dynamic Fascial Closure With Vacuum-Assisted Wound Closure and Mesh-Mediated Fascial Traction (VAWCM) Treatment of the Open Abdomen-An Updated Systematic Review.Frontiers in surgery · 2020Pooled it
- EHS clinical guidelines on the management of the abdominal wall in the context of the open or burst abdomen.Hernia : the journal of hernias and abdominal wall surgery · 2018Guideline
- [Visceral surgery in mass casualty incidents due to disasters, crises and war].Chirurgie (Heidelberg, Germany) · 2026Review
- Stepwise plication of abdominal mesh technique for open abdomen closure.Acta cirurgica brasileira · 2026Article
- Early application of abdominal re-approximation anchor system for the management of the open abdomen.Scientific reports · 2025Article
- Open abdomen versus primary closure in the management of severe abdominal sepsis: What is the right way? Results of the last 5 years of a reference center.Langenbeck's archives of surgery · 2025Article
- Entero-Cutaneous and Entero-Atmospheric Fistulas: Insights into Management Using Negative Pressure Wound Therapy.Journal of clinical medicine · 2024Review
- Evaluating a novel vertical traction device for early closure in open abdomen management: a consecutive case series.Frontiers in surgery · 2024Article
- A prospective multicentre study evaluating the outcomes of the abdominal wall dehiscence repair using posterior component separation with transversus abdominis muscle release reinforced by a retro-muscular mesh: filling a step.World journal of emergency surgery : WJES · 2023Article
- Article
- Retrospective Study of Indications and Outcomes of Open Abdomen with Negative Pressure Wound Therapy Technique for Abdominal Sepsis in a Tertiary Referral Centre.Antibiotics (Basel, Switzerland) · 2022Article
- Outcome in patients with open abdomen treatment for peritonitis: a multidomain approach outperforms single domain predictions.Journal of clinical monitoring and computing · 2022Article
- Simultaneous early surgical repair of post-cholecystectomy major bile duct injury and complex abdominal evisceration: A case report.International journal of surgery case reports · 2022Article
- Status quo of the use of DCS concepts and outcome with focus on blunt abdominal trauma : A registry-based analysis from the TraumaRegister DGU®.Langenbeck's archives of surgery · 2022Article
- Predictive factors of mortality in open abdomen for abdominal sepsis: a retrospective cohort study on 113 patients.Updates in surgery · 2021Article
- Abdominal Decompression after Cardiac Surgery: Outcome of 42 Patients with Abdominal Compartment Syndrome.World journal of surgery · 2021Article
- Long Term Outcome After Open Abdomen Treatment: Function and Quality of Life.Frontiers in surgery · 2021Article
- Prophylactic Onlay Mesh Implantation During Definitive Fascial Closure After Open Abdomen Therapy (PROMOAT): Absorbable or Non-absorbable? Methodical Description and Results of a Feasibility Study.Frontiers in surgery · 2020Article
- Entero-atmospheric fistula migration: a new management alternative for complex septic open abdomen.Anaesthesiology intensive therapy · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe open abdomen has become an accepted treatment option of critically ill patients with severe intra-abdominal conditions. Fascial closure is a particular challenge in patients with peritonitis. This study investigates whether fascial closure rates can be increased in peritonitis patients by using an algorithm that combines vacuum-assisted wound closure and mesh-mediated fascial traction. Moreover, fascial closure rates for patients with peritonitis, trauma or abdominal compartment system (ACS) are compared.
methodsData were collected prospectively from all patients who underwent open abdomen management at our institution from 2006 to 2012. All patients were treated under a standardised algorithm that combines vacuum-assisted closure and mesh placement at the fascial level.
resultsDuring the study period, 53 patients (mean age 53 years) underwent open abdomen management for a mean duration of 15 days. Indications for leaving the abdomen open were peritonitis (51 %), trauma (26 %), and ACS or abdominal wall dehiscence (23 %). The fascial closure rate was 79 % in an intention-to-treat analysis and 89 % in a per-protocol analysis. Mortality was 13 %. No patient developed an enteroatmospheric fistula or abdominal wall dehiscence after closure. The mean duration of treatment was significantly longer in peritonitis patients (20 days) than in patients without peritonitis (10 days) (p = 0.03). There were no significant differences in fascial closure rates between patients with peritonitis (87 %), trauma (85 %), and ACS or abdominal wall dehiscence (100 %) (p = 0.647).
conclusionsRegardless of the underlying pathology, high fascial closure rates can be achieved using a combination of vacuum-assisted closure and mesh-mediated fascial traction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.