ReviewPediatric nephrology (Berlin, Germany)2015
Salt intake in children and its consequences on blood pressure.
Review in Pediatric nephrology (Berlin, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 5 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Dapagliflozin and Empagliflozin in Paediatric Indications: A Systematic Review.Paediatric drugs · 2024Pooled it
- Pooled it
- The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).Hypertension research : official journal of the Japanese Society of Hypertension · 2019Guideline
- Application of Mobile Health Technologies Aimed at Salt Reduction: Systematic Review.JMIR mHealth and uHealth · 2019Pooled it
- The Diet of Preschool Children in the Mediterranean Countries of the European Union: A Systematic Review.International journal of environmental research and public health · 2016Pooled it
- Testing the efficacy of and parents' preferences for nutrition labels on children's menus from a full-service chain restaurant: results of an online experiment.Public health nutrition · 2020Trial
- Repurposing Empagliflozin for Duchenne Muscular Dystrophy-Associated Cardiomyopathy: Protocol for a Pharmacokinetics, Safety and Proof-of-Concept Trial in Children.Cardiology and therapy · 2026Article
- Mapping and Nutrient Profiles of Commercially Produced Complementary Foods in West Africa.Maternal & child nutrition · 2026Article
- Oral sodium supplementation on growth and hypertension in preterm infants: an observational cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2024Observational
- Comparison of In-Person and Virtual Implementations of an Obesity Prevention Culinary Nutrition Education Program for Family Care Providers.Obesities · 2024Article
- Dietary Strategies in the Prevention and Treatment of Hypertension in Children and Adolescents: A Narrative Review.Nutrients · 2024Review
- Salt Intake of Children and Adolescents: Influence of Socio-Environmental Factors and School Education.Nutrients · 2024Article
- Complementary feeding in infants born preterm: Aspects needing improvement.JPGN reports · 2024Article
- The Future for the Children of Tomorrow: Avoiding Salt in the First 1000 Days.Children (Basel, Switzerland) · 2024Review
- Benchmarking the nutrient composition and labelling practices of commercially produced ready-to-eat purées and meals for older infants and young children across seven Southeast Asian countries.Maternal & child nutrition · 2023Article
- Benchmarking the nutrient composition and labelling practices of dry or instant cereals for older infants and young children across seven Southeast Asian countries.Maternal & child nutrition · 2023Article
- The damaging duo: Obesity and excess dietary salt contribute to hypertension and cardiovascular disease.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Review
- Article
- Initiatives to Reduce the Content of Sodium in Food Products and Meals and Improve the Population's Health.Nutrients · 2023Review
- Salt taste threshold and contributory factors of chronic kidney disease patients: a cross-sectional study.International urology and nephrology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sodium is the most abundant extracellular cation and therefore pivotal in determining fluid balance. At the beginning of life, a positive sodium balance is needed to grow. Newborns and preterm infants tend to lose sodium via their kidneys and therefore need adequate sodium intake. Among older children and adults, however, excessive salt intake leads to volume expansion and arterial hypertension. Children who are overweight, born preterm, or small for gestational age and African American children are at increased risk of developing high blood pressure due to a high salt intake because they are more likely to be salt sensitive. In the developed world, salt intake is generally above the recommended intake also among children. Although a positive sodium balance is needed for growth during the first year of life, in older children, a sodium-poor diet seems to have the same cardiovascular protective effects as among adults. This is relevant, since: (1) a blood pressure tracking phenomenon was recognized; (2) the development of taste preferences is important during childhood; and (3) salt intake is often associated with the consumption of sugar-sweetened beverages (predisposing children to weight gain).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.