ArticleVirulence2014
Polyphosphate-mediated modulation of Campylobacter jejuni biofilm growth and stability.
Article in Virulence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- The role of cydB gene in the biofilm formation by Campylobacter jejuni.Scientific reports · 2024Article
- The role ofResearch square · 2024Article
- Identification of genes associated with environmental persistence in Campylobacter jejuni and Campylobacter coli isolates from processing in a broiler abattoir.Veterinary research communications · 2022Article
- Extracellular c-di-GMP Plays a Role in Biofilm Formation and Dispersion ofMicroorganisms · 2022Article
- Antibiofilm Potential ofApplied and environmental microbiology · 2021Article
- The biology of thermoacidophilic archaea from the order Sulfolobales.FEMS microbiology reviews · 2021Article
- The Role of Polyphosphate in Motility, Adhesion, and Biofilm Formation inMicroorganisms · 2021Article
- Molecular Mechanisms of Campylobacter Biofilm Formation and Quorum Sensing.Current topics in microbiology and immunology · 2021Review
- Transducer-Like Protein inFrontiers in microbiology · 2018Article
- Intrinsic and Extrinsic Aspects onFrontiers in microbiology · 2017Article
- Polyphosphate and associated enzymes as global regulators of stress response and virulence in Campylobacter jejuni.World journal of gastroenterology · 2016Review
- Polyphosphatase PPN1 of Saccharomyces cerevisiae: switching of exopolyphosphatase and endopolyphosphatase activities.PloS one · 2015Article
- Transducer like proteins of Campylobacter jejuni 81-176: role in chemotaxis and colonization of the chicken gastrointestinal tract.Frontiers in cellular and infection microbiology · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms increase C. jejuni's resilience to detergents, antibiotics, and environmental stressors. In these investigations, we studied the modulation of biofilm in response to phosphate related stressors. We found that the deletion of ppk1, phoX, and ppk2 (polyphosphate associated [poly P] genes) in C. jejuni modulated different stages of biofilm formation such as attached microcolonies, air-liquid biofilms, and biofilm shedding. Additionally, inorganic phosphate also modulated attached microcolonies, air-liquid biofilms, and biofilm shedding both independently of and additively in the poly P associated mutants. Furthermore, we observed that these different biofilm stages were affected by biofilm age: for example, the adherent microcolonies were maximum on day 2, while biofilm growth at the air-liquid interface and shedding was highest on day 3. Also, we observed altered calcofluor white reactive polysaccharides in poly P-associated mutants, as well as increased secretion of autoinducer-2 (AI-2) quorum sensing molecules in the ∆ppk2 mutant. Further, the polysaccharide and flagellar biosynthesis genes, that are associated with biofilm formation, were altered in these poly P-associated mutants. We conclude that the phosphate limiting condition modulates C. jejuni biofilm formation.
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