Evidence map›Paper›PMID 25126777›Full record

ArticleCell2014

A timeless but timely connection between replication and recombination.

Valérie Borde, Michael Lichten

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Association genetics of bunch weight and its component traits in East African highland banana (Musa spp. AAA group).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Valérie BordeCNRS UMR3664, Institut Curie, Centre de Recherche, Paris 75248, France. Electronic address: valerie.borde@curie.fr.
Michael LichtenLaboratory of Biochemistry and Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address: mlichten@helix.nih.gov.
Centre National de la Recherche Scientifique · FRNational Cancer Institute · US

Funding

Mechanism of Meiotic RecombinationZIABC005268 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LICHTEN, MICHAEL J · 2009 to 2023
$17.3M
Intramural NIH HHS
6 · The paper itself

Abstract

Initiation of meiotic recombination by DNA double-strand break formation is temporally coordinated with replication. Murakami and Keeney show that this coordination requires recruitment of the Dbf4-dependent kinase to the replication fork by the conserved TIM-TIPIN complex. The same mechanism may regulate other important replication-associated processes.

Indexed as

DNA Breaks, Double-StrandedDNA ReplicationMeiosisCell Cycle ProteinsProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCDC7 protein, S cerevisiaeCell Cycle ProteinsProtein Serine-Threonine KinasesREC107 protein, S cerevisiaeSaccharomyces cerevisiae Proteins

Identifiers

PMID25126777
OpenAlexW2061642475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.