Evidence map›Paper›PMID 25126521›Full record

ArticleToxicology reports2014

The RPTEC/TERT1 cell line models key renal cell responses to the environmental toxicants, benzo[a]pyrene and cadmium.

B R Simon, M J Wilson, J K Wickliffe

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Evaluation of biomarkers forToxicology research · 2020
    Article
  12. Article
  13. Article
  14. Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics.Drug metabolism and disposition: the biological fate of chemicals · 2018
    Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B R SimonGraduate Program in Biomedical Sciences, School of Medicine, Tulane University, New Orleans, LA 70112, United States of America ; Department of Global Environmental Health Sciences, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, United States of America.
M J WilsonDepartment of Global Environmental Health Sciences, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, United States of America.
J K WickliffeDepartment of Global Environmental Health Sciences, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, United States of America.
Tulane University · US

Funding

Transdisciplinary Research Consortium for Gulf Resilience on Women's HealthU19ES020677 · NIEHS · TULANE UNIVERSITY OF LOUISIANA · PI LICHTVELD, MAUREEN Y. · 2011 to 2015
$7.1M
NIEHS NIH HHS U19 ES020677
6 · The paper itself

Abstract

We have characterized initial canonical responses to two environmental toxicants, cadmium (Cd) and benzo[a]pyrene (B[a]P), in a novel

Indexed as

Benzo[a]pyreneCadmiumIn vitro immortalized renal cellRPTEC/TERT1Tox21

Identifiers

PMID25126521
PMCPMC4128258
OpenAlexW2000496441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.