Evidence map›Paper›PMID 25126384›Full record

ReviewWorld journal of stem cells2014

Endothelial progenitor cells in cardiovascular diseases.

Poay Sian Sabrina Lee, Kian Keong Poh

Abstract readReview
In one paragraph

Review in World journal of stem cells, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

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  18. Endothelial progenitor cells predict vascular damage progression in naive hypertensive patients according to sex.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
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  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Poay Sian Sabrina LeePoay Sian Sabrina Lee, Kian Keong Poh, Cardiac Department, National University Heart Centre, National University Health System, Singapore and Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Kian Keong PohPoay Sian Sabrina Lee, Kian Keong Poh, Cardiac Department, National University Heart Centre, National University Health System, Singapore and Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial dysfunction has been associated with the development of atherosclerosis and cardiovascular diseases. Adult endothelial progenitor cells (EPCs) are derived from hematopoietic stem cells and are capable of forming new blood vessels through a process of vasculogenesis. There are studies which report correlations between circulating EPCs and cardiovascular risk factors. There are also studies on how pharmacotherapies may influence levels of circulating EPCs. In this review, we discuss the potential role of endothelial progenitor cells as both diagnostic and prognostic biomarkers. In addition, we look at the interaction between cardiovascular pharmacotherapies and endothelial progenitor cells. We also discuss how EPCs can be used directly and indirectly as a therapeutic agent. Finally, we evaluate the challenges facing EPC research and how these may be overcome.

Indexed as

Cardiovascular diseasesDiabetesDyslipidemiaEndothelial progenitor cellsHypertensionStentsTherapy

Identifiers

PMID25126384
PMCPMC4131276

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.