ArticleInternational journal of clinical and experimental medicine2014
Occlusive barriers in combination with particulate Bio-Oss® graft: a pilot study on rabbit calvaria.
Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- [Comparative study of processed autogenous tooth bone and xenogeneic bovine bone in repairing an alveolar bone defect].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2018Article
- Effect of Multilaminate Small Intestinal Submucosa as a Barrier Membrane on Bone Formation in a Rabbit Mandible Defect Model.BioMed research international · 2018Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to histologically evaluate the potential for vertical bone augmentation of the Bio-Oss® graft compared to a blood clot in conjunction with an occlusive barrier in the rabbit calvaria defect model. Metallic dome shaped barriers with 4.5 mm width and 3.5 mm height were positioned in six adult rabbit skulls. At the right side, the barrier was filled with Bio-Oss®, and the left side was filled with a blood clot. After a healing period of three months, the animals were sacrificed, and the samples were prepared for histological and histomorphometric analyses. The total mineralized area (TMA) as well as the newly formed bone (NBA) was calculated as the percentage of the bone augmentation inside the metallic barriers, and parametric statistical analysis was used to describe the findings. The samples with blood clots exhibited significantly less TMA formation than the Bio-Oss® group. However, the difference in the amount of NBA was not statistically significant. Furthermore, the Bio-Oss® specimens exhibited remaining graft particles within the sample. In conclusion, the barriers filled with Bio-Oss® exhibited significantly higher TMA than those with only blood clots, and the remaining Bio-Oss® particles were integrated into newly formed bone tissue to fill the spaces and promote a greater volume than the samples from the blood clot groups.
Indexed as
Identifiers
25126169PMC4132133W106525082What OpenQuestion holds
Registered trials
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