Evidence map›Paper›PMID 25126069›Full record

ArticleFrontiers in neuroinformatics2014

Pydpiper: a flexible toolkit for constructing novel registration pipelines.

Miriam Friedel, Matthijs C van Eede, Jon Pipitone, M Mallar Chakravarty, Jason P Lerch

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

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  8. Neurodevelopmental Impacts of Ketamine and Alfaxalone Anesthesia Evaluated with Mouse MRI.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025
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  15. Sex chromosomes and hormones independently influence healthy brain development but act similarly after cranial radiation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
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  17. Article
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Miriam FriedelMouse Imaging Centre, Hospital for Sick Children Toronto, ON, Canada.
Matthijs C van EedeMouse Imaging Centre, Hospital for Sick Children Toronto, ON, Canada.
Jon PipitoneKimel Family Translational Imaging-Genetics Research Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health Toronto, ON, Canada.
M Mallar ChakravartyKimel Family Translational Imaging-Genetics Research Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health Toronto, ON, Canada ; Department of Psychiatry, Institute of Biomaterials and Biomedical Engineering, University of Toronto Toronto, ON, Canada ; Rotman Research Institute Toronto, ON, Canada.
Jason P LerchMouse Imaging Centre, Hospital for Sick Children Toronto, ON, Canada ; Department of Medical Biophysics, University of Toronto Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using neuroimaging technologies to elucidate the relationship between genotype and phenotype and brain and behavior will be a key contribution to biomedical research in the twenty-first century. Among the many methods for analyzing neuroimaging data, image registration deserves particular attention due to its wide range of applications. Finding strategies to register together many images and analyze the differences between them can be a challenge, particularly given that different experimental designs require different registration strategies. Moreover, writing software that can handle different types of image registration pipelines in a flexible, reusable and extensible way can be challenging. In response to this challenge, we have created Pydpiper, a neuroimaging registration toolkit written in Python. Pydpiper is an open-source, freely available software package that provides multiple modules for various image registration applications. Pydpiper offers five key innovations. Specifically: (1) a robust file handling class that allows access to outputs from all stages of registration at any point in the pipeline; (2) the ability of the framework to eliminate duplicate stages; (3) reusable, easy to subclass modules; (4) a development toolkit written for non-developers; (5) four complete applications that run complex image registration pipelines "out-of-the-box." In this paper, we will discuss both the general Pydpiper framework and the various ways in which component modules can be pieced together to easily create new registration pipelines. This will include a discussion of the core principles motivating code development and a comparison of Pydpiper with other available toolkits. We also provide a comprehensive, line-by-line example to orient users with limited programming knowledge and highlight some of the most useful features of Pydpiper. In addition, we will present the four current applications of the code.

Indexed as

image registrationneuroimagingpipelinePythonsoftware

Identifiers

PMID25126069
PMCPMC4115634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.