Evidence map›Paper›PMID 25125589›Full record

ArticleRheumatology (Oxford, England)2015

Impact of musculoskeletal pain on insomnia onset: a prospective cohort study.

Nicole K Y Tang, John McBeth, Kelvin P Jordan, Milisa Blagojevic-Bucknall, Peter Croft, Ross Wilkie

Abstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Impact of Life-Context Factors on Chronic Rhinosinusitis 22-Item Sinonasal Outcomes Test: Systematic Review + Meta-Analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
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  9. Chronic Lumbar Pain and Insomnia in College-Aged Students.Healthcare (Basel, Switzerland) · 2022
    Article
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  11. Risk factors of persistent insomnia among survivors of traumatic injury: a retrospective cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicole K Y TangDepartment of Psychology, University of Warwick, Coventry and Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire, UK. Department of Psychology, University of Warwick, Coventry and Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire, UK. n.tang@warwick.ac.uk.
John McBethDepartment of Psychology, University of Warwick, Coventry and Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire, UK.
Kelvin P JordanDepartment of Psychology, University of Warwick, Coventry and Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire, UK.
Milisa Blagojevic-BucknallDepartment of Psychology, University of Warwick, Coventry and Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire, UK.
Peter CroftDepartment of Psychology, University of Warwick, Coventry and Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire, UK.
Ross WilkieDepartment of Psychology, University of Warwick, Coventry and Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Staffordshire, UK.

Funding

Medical Research Council G0501798Medical Research Council G9900220
6 · The paper itself

Abstract

objectivePain, the most common manifestation of rheumatological conditions, is highly prevalent among older adults, with worse health outcomes found in those with co-morbid insomnia. Proactive prevention of insomnia may reduce the overall disease burden of pain and rheumatological conditions. To inform such development, this study examined the role of pain, physical limitation and reduced social participation in predicting and mediating insomnia onset.

methodsA prospective cohort study was conducted involving 6676 individuals ≥50 years of age who completed questionnaires at baseline and a 3-year follow-up. Participants were classified into none, some and widespread pain according to the ACR criteria. Logistic regression was used to examine the relationship between baseline pain and insomnia onset at 3 years. Path analysis was used to test for the mediating role of physical limitation and social participation restriction.

resultsSome [adjusted odds ratio (AOR) 1.57 (95% CI 1.15, 2.13)] and widespread [2.13 (1.66, 3.20)] pain increased the risk of insomnia onset at 3 years, after adjusting for age, gender, socio-economic class, education, anxiety, depression, sleep and co-morbidity at baseline. The combination of physical limitation and reduced social participation explained up to 68% of the effect of some pain on insomnia onset and 66% of the effect of widespread pain on insomnia onset.

conclusionThere was a dose-response association between the extent of pain at baseline and insomnia onset at 3 years that was substantially mediated by physical limitation and reduced social participation. Targeting physical limitation and social participation in older people with pain may buffer co-morbid insomnia, reducing the overall disease burden.

Indexed as

AgedFemaleHumansInterpersonal RelationsMaleMiddle AgedMusculoskeletal PainPersons with DisabilitiesProspective StudiesSleep Initiation and Maintenance Disorderscohort studyinsomniamusculoskeletalphysical functionsleepsocial participationwidespread pain

Identifiers

PMID25125589
PMCPMC4301708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.