ArticleBMJ open2014
Reduction in stillbirths at term after new birth induction paradigm: results of a national intervention.
Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Global trends in prevalence of maternal overweight and obesity: A systematic review and meta-analysis of routinely collected data retrospective cohorts.International journal of population data science · 2024Pooled it
- Continued versus discontinued oxytocin after the active phase of labor: An updated systematic review and meta-analysis.PloS one · 2022Pooled it
- Membrane sweeping for induction of labour.The Cochrane database of systematic reviews · 2020Pooled it
- Risks of stillbirth and neonatal death with advancing gestation at term: A systematic review and meta-analysis of cohort studies of 15 million pregnancies.PLoS medicine · 2019Pooled it
- Labor induction at 41Acta obstetricia et gynecologica Scandinavica · 2024Trial
- Continued versus discontinued oxytocin stimulation in the active phase of labour (CONDISOX): double blind randomised controlled trial.BMJ (Clinical research ed.) · 2021Trial
- Term stillbirths in Eastern Uganda: a community-based prospective cohort study.Global health action · 2025Article
- Perinatal death in the Nordic countries in relation to gestational age: The impact of registration practice.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Comparison of two labor induction regimens with intravaginal misoprostol 25 μg and adverse perinatal outcomes.Revista da Associacao Medica Brasileira (1992) · 2024Article
- The Correct Indication to Induce Labour in a Swiss Cantonal Hospital.Journal of clinical medicine · 2023Article
- Critical analysis of risk factors for intrapartum fetal death.Archives of gynecology and obstetrics · 2023Article
- The prevalence and associated factors of success of labor induction in Hargeisa maternity hospitals, Hargeisa Somaliland 2022: a hospital-based cross-sectional study.BMC pregnancy and childbirth · 2023Article
- Stillbirth incidence and determinants in a tertiary health facility in the Volta Region of Ghana.PloS one · 2023Article
- Article
- Risk of complications in the late vs early days of the 42nd week of pregnancy: A nationwide cohort study.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Prevalence and factors associated with failed induction of labor in Worabe Comprehensive Specialized Hospital, Southern Ethiopia.PloS one · 2022Article
- Pregnancy-Related and Perinatal Outcomes in Women With Multiple Sclerosis: A Nationwide Danish Cross-sectional Study.Neurology. Clinical practice · 2021Article
- Article
- Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age.Journal of women's health (2002) · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe risk of fetal death increases steeply after 42 gestational weeks. Since 2009, Denmark has had a more proactive policy including prevention of prolonged pregnancy, and early intervention in women with diabetes, preeclampsia, high body mass index and of a higher age group. The aim of this study was to describe the development in fetal deaths with this more proactive birth induction practice, and to identify and quantify contributing factors for this development.
designNational cohort study.
settingDenmark.
participantsDelivering women in Denmark, 1 January 2000 to 31 December 2012. OUTCOME MEASURES: Stillbirths per 1000 women at risk (prospective risk of stillbirth) and per 1000 newborn from 37 and 40 gestational weeks, respectively, through the study period.
resultsDuring the study period, 829,165 children were live born and 3770 (0.45%) stillborn. Induction of labour increased from 12.4% in year 2000 to 25.1% in 2012 (p<0.001), and the percentage of children born at or after 42 weeks decreased from 8.0% to 1.5% (p<0.001). Through the same period, the prospective risk of stillbirth after 37 weeks fell from 0.70 to 0.41/1000 ongoing pregnancies (p<0.001), and from 2.4 to 1.4/1000 newborn (p<0.001). The regression analysis confirmed the inverse association between year of birth and risk of stillbirth. The lowest risk was observed in the years 2011-2012 as compared with years 2000-2002 with a fully adjusted HR of 0.69 (95% CI 0.57 to 0.83). The general earlier induction, the focused earlier induction of women with body mass index >30, twins, and of women above 40 years and a halving of smoking pregnant women were all independent contributing factors for the decrease.
conclusionsA gradually more proactive and differential earlier labour induction practice is likely to have mainly been responsible for the substantial reduction in stillbirths in Denmark.
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