Evidence map›Paper›PMID 25125219›Full record

ArticleBMC gastroenterology2014

Dietary guideline adherence for gastroesophageal reflux disease.

Ai Kubo, Gladys Block, Charles P Quesenberry, Patricia Buffler, Douglas A Corley

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ai Kubo
Gladys Block
Charles P Quesenberry
Patricia Buffler
Douglas A CorleyKaiser Permanente Division of Research, University of California, San Francisco, 2000 Broadway, Oakland, CA 94612, USA. douglas.corley@kp.org.
University of California, San Francisco · USBerkeley Public Health Division · USKaiser Permanente · USUniversity of California, Berkeley · US

Funding

Epidemiology and Incidence of Barrett's EsophagusR01DK063616 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORLEY, DOUGLAS ALLEN · 2002 to 2010
$2.6M
ETIOLOGIES/SURVEILLANCE OF BARRETT'S ESOPHAGUSK08DK002697 · NIDDK · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI CORLEY, DOUGLAS ALLEN · 2000 to 2004
$599k
The effects of Diet on Barrett's esophagus and gastroesophageal reflux diseaseF32DK081271 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUBO, AI · 2008 to 2009
$92k
NIDDK NIH HHS F32 DK081271NIDDK NIH HHS K08 DK02697NIDDK NIH HHS R01 DK63616
6 · The paper itself

Abstract

backgroundGastroesophageal reflux disease (GERD) is the most common gastrointestinal disease, and the cost of health care and lost productivity due to GERD is extremely high. Recently described side effects of long-term acid suppression have increased the interest in nonpharmacologic methods for alleviating GERD symptoms. We aimed to examine whether GERD patients follow recommended dietary guidelines, and if adherence is associated with the severity and frequency of reflux symptoms.

methodsWe conducted a population-based cross-sectional study within the Kaiser Permanente Northern California population, comparing 317 GERD patients to 182 asymptomatic population controls. All analyses adjusted for smoking and education.

resultsGERD patients, even those with moderate to severe symptoms or frequent symptoms, were as likely to consume tomato products and large portion meals as GERD-free controls and were even more likely to consume soft drinks and tea [odds ratio (OR) = 2.01 95% confidence interval (CI) 1.12-3.61; OR = 2.63 95% CI 1.24-5.59, respectively] and eat fried foods and high fat diet. The only reflux-triggering foods GERD patients were less likely to consume were citrus and alcohol [OR = 0.59; 95% CI: 0.35-0.97 for citrus; OR = 0.41 95% CI 0.19-0.87 for 1 + drink/day of alcohol]. The associations were similar when we excluded users of proton pump inhibitors.

conclusionsGERD patients consume many putative GERD causing foods as frequently or even more frequently than asymptomatic patients despite reporting symptoms. These findings suggest that, if dietary modification is effective in reducing GERD, substantial opportunities for nonpharmacologic interventions exist for many GERD patients.

Indexed as

Feeding BehaviorAdultAgedAlcohol DrinkingCarbonated BeveragesCase-Control StudiesCitrusCross-Sectional StudiesDiet, Fat-RestrictedDiet, High-FatFemaleGastroesophageal RefluxHeartburnHumansMaleMiddle AgedTea

Identifiers

PMID25125219
PMCPMC4139138
OpenAlexW2115844095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.