Evidence map›Paper›PMID 25124827›Full record

ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2014

Molecular imaging of plaque vulnerability.

Sina Tavakoli, Aseem Vashist, Mehran M Sadeghi

Abstract readCase ReportsReview
In one paragraph

Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Imaging Immunometabolism in Atherosclerosis.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021
    Review
  3. Review
  4. Review
  5. Hype or HopeCirculation. Cardiovascular imaging · 2019
    Article
  6. Technical considerations for quantification ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  7. Updates on Approaches for Studying Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2019
    Article
  8. Review
  9. Review
  10. Molecular Imaging of the Heart.Comprehensive Physiology · 2019
    Review
  11. Article
  12. Molecular imaging of calcific aortic valve disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Review
  13. Article
  14. Article
  15. Editorial in response to: PET/CT evaluation ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  16. Cardiovascular PET/MR imaging: Quo Vadis?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Review
  17. Review
  18. Review
  19. Molecular cardiovascular imaging is ready for prime time: almost there.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sina TavakoliDepartment of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Aseem Vashist
Mehran M Sadeghi

Funding

Imaging protease activation in calcific aortic valve diseaseR01HL114703 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2012 to 2016
$2.0M
Macrophage elastase and its imaging in vascular inflammation and remodelingR01HL112992 · NHLBI · YALE UNIVERSITY · PI SADEGHI, MEHRAN M · 2013 to 2016
$2.0M
Molecular Imaging of Protease Activation in AneurysmI01BX001750 · VA · VA CONNECTICUT HEALTHCARE SYSTEM · PI SADEGHI, MEHRAN M · 2013 to 2016
–
BLRD VA I01 BX001750NHLBI NIH HHS R01 HL112992NHLBI NIH HHS R01 HL114703
6 · The paper itself

Abstract

Over the past decade, significant progress has been made in the development of novel imaging strategies focusing on the biology of the vessel wall for identification of vulnerable plaques. While the majority of these studies are still in the pre-clinical stage, few techniques (e.g., (18)F-FDG and (18)F-NaF PET imaging) have already been evaluated in clinical studies with promising results. Here, we will briefly review the pathobiology of atherosclerosis and discuss molecular imaging strategies that have been developed to target these events, with an emphasis on mechanisms that are associated with atherosclerotic plaque vulnerability.

Indexed as

AtherosclerosisHumansImage EnhancementImage Interpretation, Computer-AssistedMaleMiddle AgedMolecular ImagingRadiopharmaceuticalsRisk AssessmentTomography, Emission-ComputedRadiopharmaceuticals

Identifiers

PMID25124827
PMCPMC4229449

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.