Evidence map›Paper›PMID 25124257›Full record

Trial reportJournal of substance abuse treatment

A therapeutic workplace for the long-term treatment of drug addiction and unemployment: eight-year outcomes of a social business intervention.

Will M Aklin, Conrad J Wong, Jacqueline Hampton, Dace S Svikis, Maxine L Stitzer, George E Bigelow, Kenneth Silverman

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance abuse treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00249457 (A Therapeutic Workplace for Drug Abusers), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00249457 nacompletednot on this map

A Therapeutic Workplace for Drug Abusers

TypeinterventionalSponsorJohns Hopkins UniversityRan1996 to 2006Enrolled40ConditionsBehavior, Addictive, Cocaine Abuse, Cocaine Dependence, Heroin DependenceArmsContingency management
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The protective effect of operant social reward on cocaine self-administration, choice, and relapse is dependent on delay and effort for the social reward.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  11. Review
  12. Misalignment of Stakeholder Incentives in the Opioid Crisis.International journal of environmental research and public health · 2020
    Review
  13. Article
  14. Article
  15. Abstinence-dependent dissociable central amygdala microcircuits control drug craving.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Will M AklinJohns Hopkins University School of Medicine.
Conrad J WongJohns Hopkins University School of Medicine.
Jacqueline HamptonJohns Hopkins University School of Medicine.
Dace S SvikisJohns Hopkins University School of Medicine.
Maxine L StitzerJohns Hopkins University School of Medicine.
George E BigelowJohns Hopkins University School of Medicine.
Kenneth SilvermanJohns Hopkins University School of Medicine. Electronic address: ksilverm@jhmi.edu.

Funding

HUMAN BEHAVIORAL PHARMACOLOGY OF SUBSTANCE ABUSET32DA007209 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Eric C. Strain, Elise M Weerts · 1985 to 2026
$12.9M
A REINFORCEMENT-BASED THERATPEUTIC WORKPLACER01DA013107 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SILVERMAN, KENNETH · 1999 to 2006
$3.2M
THERAPEUTIC WORKPLACE TO PREVENT HIV TRANSMISSIONR01DA012564 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SILVERMAN, KENNETH · 1999 to 2003
$1.9M
THERAPEUTIC WORKPLACE FOR DRUG ABUSERSR01DA009426 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SILVERMAN, KENNETH · 1996 to 1998
–
NIDA NIH HHS R01 DA012564NIDA NIH HHS R01 DA013107NIDA NIH HHS R01 DA09426NIDA NIH HHS R01 DA12564NIDA NIH HHS R01 DA13107NIDA NIH HHS T32 DA007209
6 · The paper itself

Abstract

This study evaluated the long-term effects of a therapeutic workplace social business on drug abstinence and employment. Pregnant and postpartum women (N = 40) enrolled in methadone treatment were randomly assigned to a therapeutic workplace or usual care control group. Therapeutic workplace participants could work weekdays in training and then as employees of a social business, but were required to provide drug-free urine samples to work and maintain maximum pay. Three-year outcomes were reported previously. This paper reports 4- to 8-year outcomes. During year 4 when the business was open, therapeutic workplace participants provided significantly more cocaine- and opiate-negative urine samples than controls; reported more days employed, higher employment income, and less money spent on drugs. During the 3 years after the business closed, therapeutic workplace participants only reported higher income than controls. A therapeutic workplace social business can maintain long-term abstinence and employment, but additional intervention may be required to sustain effects.

Indexed as

EmploymentWorkplaceAdultFemaleHumansMethadoneNarcoticsPostpartum PeriodPregnancyReinforcement, PsychologySubstance Abuse DetectionSubstance-Related DisordersTreatment OutcomeUnemploymentMethadoneNarcoticsCocaineContingency managementEmploymentHeroinIncentiveMethadoneSocial business

Identifiers

PMID25124257
PMCPMC4176507

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.