ReviewInternational wound journal2016
Vitamin E and wound healing: an evidence-based review.
Review in International wound journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- The Roles of Micronutrition and Nutraceuticals in Enhancing Wound Healing and Tissue Regeneration: A Systematic Review.Molecules (Basel, Switzerland) · 2025Pooled it
- The Effect of Aloe vera on the Healing of Diabetic Foot Ulcer: A Randomized, Double-blind Clinical Trial.Current drug discovery technologies · 2024Trial
- Vitamin E as alternative local treatment in genitourinary syndrome of menopause: a randomized controlled trial.International urogynecology journal · 2019Trial
- Vitamins and Chronic Wounds: How Altered Pharmacokinetics and Comorbidities Contribute to Vitamin Deficiencies.Basic & clinical pharmacology & toxicology · 2026Review
- Arginine-Enriched Oral Nutritional Supplement as an Adjunct to Standard of Care in the Treatment of Recalcitrant Venous Leg Ulcers.International wound journal · 2026Article
- Article
- Nanoencapsulated senotherapeutic compounds targeting connexin-43 for enhanced wound healing.iScience · 2026Article
- Rethinking Chronic Wound Treatment: Unlocking the Potential of Combination Products for an Unmet Multifactorial Need: A Review Study.Health science reports · 2026Article
- Preliminary In Vitro Evaluation of Vitamin E (α-Tocopherol) Incorporation on Cytotoxicity, Antifungal Activity, and Surface Roughness of Denture Acrylic Soft Liner.International journal of dentistry · 2026Article
- Fat-soluble vitamins as biomarkers of nutritional status and their relation with complications in polytrauma patients.Nutrition and health · 2025Observational
- Natural Products for Improving Soft Tissue Healing: Mechanisms, Innovations, and Clinical Potential.Pharmaceutics · 2025Review
- Vitamin E incorporated in Carboxymethyl Cellulose-Gelatin Hydrogel Increases Wound Healing.International journal of molecular and cellular medicine · 2025Article
- Pressure Ulcers and Nutrients: From Established Evidence to Gaps in Knowledge.Current medicinal chemistry · 2025Review
- Carbomer Hydrogels with Microencapsulated α-Tocopherol: Focus on the Biocompatibility of the Microcapsules, Topical Application Attributes, and In Vitro Release Study.Pharmaceutics · 2024Article
- Pharmacotherapy for Keloids and Hypertrophic Scars.International journal of molecular sciences · 2024Review
- Plant-Derived Bioactive Compounds: Exploring Neuroprotective, Metabolic, and Hepatoprotective Effects for Health Promotion and Disease Prevention.Pharmaceutics · 2024Review
- Progress in the Use of Hydrogels for Antioxidant Delivery in Skin Wounds.Pharmaceutics · 2024Review
- Natural Compounds in Non-Melanoma Skin Cancer: Prevention and Treatment.Molecules (Basel, Switzerland) · 2024Review
- Neuroprotective effect ofFrontiers in pharmacology · 2024Article
- Fabrication and evaluation of vitamin doped Zno/AgNPs nanocomposite based wheat gluten films: a promising findings for burn wound treatment.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin E has been demonstrated to modulate cellular signalling, gene expression and affect wounds infected with methicillin-resistant Staphylococcus aureus (MRSA), thus influencing wound healing. This evidence-based review aimed to identify and evaluate current research assessing the properties of vitamin E in relation to wound healing, through its role as an antioxidant and its influence on connective tissue growth factor (CTGF), MRSA and gene transcription. Literature dated from 1996 to 2012, published in English, involving either animals or adult humans with an acute or chronic wound were included. The databases that contained relevant articles were narrowed down to four, and a total of 33 identified studies were included. The literature review revealed that there is a significant dearth of robust studies establishing the effects of vitamin E on wound healing, and further research is clearly warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.