Evidence map›Paper›PMID 25124015›Full record

ReviewJACC. Cardiovascular imaging2014

Noninvasive imaging of cardiovascular injury related to the treatment of cancer.

Suwat Kongbundansuk, W Gregory Hundley

Open access · greenAbstract readReview
In one paragraph

Review in JACC. Cardiovascular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Risk Factors for Anthracycline-Induced Cardiotoxicity.Frontiers in cardiovascular medicine · 2021
    Pooled it
  2. Trial
  3. Article
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  7. Review
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  13. Review
  14. Review
  15. Imaging of Chemotherapy-Induced Acute Cardiotoxicity withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
  16. Article
  17. Review
  18. Review
  19. Cardiovascular Disease in Survivors of Childhood Cancer: Insights Into Epidemiology, Pathophysiology, and Prevention.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Suwat KongbundansukDepartment of Internal Medicine (Section on Cardiology), Wake Forest School of Medicine, Winston-Salem, North Carolina.
W Gregory HundleyDepartment of Internal Medicine (Section on Cardiology), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina. Electronic address: ghundley@wakehealth.edu.
Wake Forest University · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Preventing Anthracycline Cardiovascular Toxicity with StatinsR01HL118740 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2013 to 2018
$4.2M
Vascular Stiffness and Pulmonary CongestionR01HL076438 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2007 to 2011
$3.2M
Early Imaging Detection of CV Injury after CancerR01CA167821 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY, JOLLY, MARIE-PIERRE · 2012 to 2016
$2.5M
Optimized CMR imaging of chemotherapy cardiotoxicityR33CA121296 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2007 to 2009
$716k
Multidisciplinary Training in Cardiovascular ImagingT32HL091824 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HUNDLEY, WILLIAM GREGORY · 2009 to 2013
$707k
Advanced Non-Contrast Imaging for Cardiotoxicity Detection after CancerR43CA174261 · NCI · ALBUS IMAGING LLC · PI GOODWIN, HOLLY, HUNDLEY, WILLIAM GREGORY · 2013 to 2013
$300k
NCI NIH HHS P30 CA012197NCI NIH HHS P30 CA12197NCI NIH HHS R01 CA167821NCI NIH HHS R33 CA121296NCI NIH HHS R43 CA174261NHLBI NIH HHS R01 HL076438NHLBI NIH HHS R01 HL118740NHLBI NIH HHS T32 HL091824PHS HHS BCTR0707769
6 · The paper itself

Abstract

The introduction of multiple treatments for cancer, including chemotherapeutic agents and radiation therapy, has significantly reduced cancer-related morbidity and mortality. However, these therapies can promote a variety of toxicities, among the most severe being the ones involving the cardiovascular system. Currently, for many surviving cancer patients, cardiovascular (CV) events represent the primary cause of morbidity and mortality. Recent data suggest that CV injury occurs early during cancer treatment, creating a substrate for subsequent cardiovascular events. Researchers have investigated the utility of noninvasive imaging strategies to detect the presence of CV injury during and after completion of cancer treatment because it starts early during cancer therapy, often preceding the development of chemotherapy or cancer therapeutics related cardiac dysfunction. In this State-of-the-Art Paper, we review the utility of current clinical and investigative CV noninvasive modalities for the identification and characterization of cancer treatment-related CV toxicity.

Indexed as

Antineoplastic AgentsCardiovascular DiseasesDiagnostic ImagingHumansMultimodal ImagingNeoplasmsPractice Guidelines as TopicPredictive Value of TestsRadiation InjuriesRadiotherapyRisk FactorsAntineoplastic Agentscardiovascular imagingchemotherapy-related cardiotoxicitynoninvasive imaging

Identifiers

PMID25124015
PMCPMC4183055
OpenAlexW2003800647

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.