Evidence map›Paper›PMID 25123085›Full record

ArticleVeterinary microbiology2014

Genetic diversity of porcine group A rotavirus strains in the UK.

Rebecca Chandler-Bostock, Laura R Hancox, Sameena Nawaz, Oliver Watts, Miren Iturriza-Gomara, Kenneth H Mellits, Kenneth M Mellits

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Veterinary microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

  • Erratum issued
    Mellits, Kenneth M [corrected to Mellits, Kenneth H]
5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rebecca Chandler-BostockUniversity of Nottingham, School of Biosciences, Division of Food Science, Sutton Bonington Campus, Loughborough LE12 5RD, UK.
Laura R HancoxUniversity of Nottingham, School of Biosciences, Division of Food Science, Sutton Bonington Campus, Loughborough LE12 5RD, UK.
Sameena NawazVirus Reference Department, Public Health England, London, NW9 5HT, UK.
Oliver WattsUniversity of Nottingham, School of Biosciences, Division of Food Science, Sutton Bonington Campus, Loughborough LE12 5RD, UK.
Miren Iturriza-GomaraVirus Reference Department, Public Health England, London, NW9 5HT, UK.
Kenneth H Mellits
Kenneth M MellitsUniversity of Nottingham, School of Biosciences, Division of Food Science, Sutton Bonington Campus, Loughborough LE12 5RD, UK. Electronic address: ken.mellits@nottingham.ac.uk.
University of Nottingham · GBPublic Health England · GB

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

Rotavirus is endemic in pig farms where it causes a loss in production. This study is the first to characterise porcine rotavirus circulating in UK pigs. Samples from diarrheic pigs with rotavirus enteritis obtained between 2010 and 2012 were genotyped in order to determine the diversity of group A rotavirus (GARV) in UK pigs. A wide range of rotavirus genotypes were identified in UK pigs: six G types (VP7); G2, G3, G4, G5, G9 and G11 and six P types (VP4); P[6], P[7], P[8], P[13], P[23], and P[32]. With the exception of a single P[8] isolate, there was less than 95% nucleotide identity between sequences from this study and any available rotavirus sequences. The G9 and P[6] genotypes are capable of infecting both humans and pigs, but showed no species cross-over within the UK as they were shown to be genetically distinct, which suggested zoonotic transmission is rare within the UK. We identified the P[8] genotype in one isolate, this genotype is almost exclusively found in humans. The P[8] was linked to a human Irish rotavirus isolate in the same year. The discovery of human genotype P[8] rotavirus in a UK pig confirms this common human genotype can infect pigs and also highlights the necessity of surveillance of porcine rotavirus genotypes to safeguard human as well as porcine health.

Indexed as

Genetic VariationPhylogenyAnimalsBase SequenceGenotypeHumansMolecular Sequence DataRetrospective StudiesRotavirusRotavirus InfectionsSwineSwine DiseasesUnited KingdomViral ProteinsViral ProteinsPhylogeneticPorcineRotavirusZoonosis

Identifiers

PMID25123085
PMCPMC4158422
OpenAlexW2142371794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.