Evidence map›Paper›PMID 25122623›Full record

ArticleeLife2014

Cryo-EM enters a new era.

Werner Kühlbrandt

Open access · goldAbstract readComment
In one paragraph

Article in eLife, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed
47.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 245 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. A structural atlas of druggable sites on NaChannels (Austin, Tex.) · 2024
    Review
  10. Review
  11. Article
  12. Review
  13. The myth of high-resolution liquid phase biological electron microscopy.Protein science : a publication of the Protein Society · 2024
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Sample Preparation for Electron Cryo-Microscopy of Macromolecular Machines.Advances in experimental medicine and biology · 2024
    Article
  19. Cryo-electron microscopy-based drug design.Frontiers in molecular biosciences · 2024
    Review
  20. Article

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Werner KühlbrandtWerner Kuehlbrandt is in the Department of Structural Biology, Max Planck Institute of Biophysics, Frankfurt, Germany werner.kuehlbrandt@biophys.mpg.de.
Max Planck Institute of Biophysics · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in detector hardware and image-processing software have led to a revolution in the use of electron cryo-microscopy to determine complex molecular structures at high resolution.

Indexed as

AlgorithmsAmyloid Precursor Protein SecretasesAnimalsbeta-GalactosidaseCryoelectron MicroscopyElectron Transport Complex IHumansRibosomesAmyloid Precursor Protein Secretasesbeta-GalactosidaseElectron Transport Complex ICryo-EMimage analysismicoscopysingle-particle analysis

Identifiers

PMID25122623
PMCPMC4131193
OpenAlexW2127697948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.