Evidence map›Paper›PMID 25122539›Full record

ArticlePLoS genetics2014

Patterns of admixture and population structure in native populations of Northwest North America.

Paul Verdu, Trevor J Pemberton, Romain Laurent, Brian M Kemp, Angelica Gonzalez-Oliver, Clara Gorodezky, Cris E Hughes, Milena R Shattuck, Barbara Petzelt, Joycelynn Mitchell and 6 more

Open access · goldAbstract read
In one paragraph

Article in PLoS genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 102 citations in OpenAlex.

  1. Article
  2. Genetic and genomic insights of the Comcáac people.Journal of community genetics · 2025
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  11. Ancient and modern genomics of the Ohlone Indigenous population of California.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Human genetic admixture.PLoS genetics · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. FTheoretical population biology · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 4 countries.

Paul VerduCNRS-MNHN-University Paris Diderot-Sorbonne Paris Cité, UMR7206 Eco-Anthropology and Ethno-Biology, Paris, France.
Trevor J PembertonDepartment of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.
Romain LaurentCNRS-MNHN-University Paris Diderot-Sorbonne Paris Cité, UMR7206 Eco-Anthropology and Ethno-Biology, Paris, France.
Brian M KempDepartment of Anthropology and School of Biological Sciences, Washington State University, Pullman, Washington, United States of America.
Angelica Gonzalez-OliverDepartmento de Biología Celular, Facultad de Ciencias, Universidad Nacional Autonóma de México, Mexico City, Mexico.
Clara GorodezkyDepartment of Immunology and Immunogenetics, Instituto de Diagnóstico y Referencia Epidemiológicos, Secretary of Health, Mexico City, Mexico.
Cris E HughesDepartment of Anthropology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
Milena R ShattuckDepartment of Anthropology, New York University, New York, New York, United States of America.
Barbara PetzeltMetlakatla Treaty Office, Metlakatla, British Columbia, Canada.
Joycelynn MitchellMetlakatla Treaty Office, Metlakatla, British Columbia, Canada.
Harold HarryStswecem'c/Xgat'tem Band, British Columbia, Canada.
Theresa WilliamSplatsin Band Office, Enderby, British Columbia, Canada.
Rosita WorlSeaalaska Heritage Institute, Juneau, Alaska, United States of America.
Jerome S CybulskiCanadian Museum of History, Gatineau, Quebec, Canada.
Noah A RosenbergDepartment of Biology, Stanford University, Stanford, California, United States of America.
Ripan S MalhiDepartment of Anthropology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America; Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
University of Illinois Urbana-Champaign · USNew York University · USSorbonne Paris Cité · FRStanford University · USUniversidad Nacional Autónoma de México · MXUniversité Paris Cité · FRUniversity of Manitoba · CAWashington State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The initial contact of European populations with indigenous populations of the Americas produced diverse admixture processes across North, Central, and South America. Recent studies have examined the genetic structure of indigenous populations of Latin America and the Caribbean and their admixed descendants, reporting on the genomic impact of the history of admixture with colonizing populations of European and African ancestry. However, relatively little genomic research has been conducted on admixture in indigenous North American populations. In this study, we analyze genomic data at 475,109 single-nucleotide polymorphisms sampled in indigenous peoples of the Pacific Northwest in British Columbia and Southeast Alaska, populations with a well-documented history of contact with European and Asian traders, fishermen, and contract laborers. We find that the indigenous populations of the Pacific Northwest have higher gene diversity than Latin American indigenous populations. Among the Pacific Northwest populations, interior groups provide more evidence for East Asian admixture, whereas coastal groups have higher levels of European admixture. In contrast with many Latin American indigenous populations, the variance of admixture is high in each of the Pacific Northwest indigenous populations, as expected for recent and ongoing admixture processes. The results reveal some similarities but notable differences between admixture patterns in the Pacific Northwest and those in Latin America, contributing to a more detailed understanding of the genomic consequences of European colonization events throughout the Americas.

Indexed as

Genetics, PopulationGenomicsAsian PeopleDNA, MitochondrialHaplotypesHumansNorth AmericaPolymorphism, Single NucleotideWhite PeopleDNA, Mitochondrial

Identifiers

PMID25122539
PMCPMC4133047
OpenAlexW1993462529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.