ArticleAmerican journal of public health2014
Epigenome: biosensor of cumulative exposure to chemical and nonchemical stressors related to environmental justice.
Article in American journal of public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Radiation effects research foundation-a view to the future.Carcinogenesis · 2025Article
- Socioeconomic and racial-ethnic disparities in flame retardant exposure and executive function skills in preschool children.Environmental health : a global access science source · 2025Article
- Linking Prenatal Environmental Exposures to Lifetime Health with Epigenome-Wide Association Studies: State-of-the-Science Review and Future Recommendations.Environmental health perspectives · 2023Review
- General and Specific Factors of Environmental Stress and Their Associations With Brain Structure and Dimensions of Psychopathology.Biological psychiatry global open science · 2023Article
- Vitamin D status in relation to inflammatory risk and albuminuria associated with polycyclic aromatic hydrocarbon exposure in the US population.Archives of environmental & occupational health · 2023Article
- Understanding Health Inequalities Through the Lens of Social Epigenetics.Annual review of public health · 2022Review
- The Interplay of Environmental Exposures and Mental Health: Setting an Agenda.Environmental health perspectives · 2022Review
- Climate change, human health, and the exposome: Utilizing OMIC technologies to navigate an era of uncertainty.Frontiers in public health · 2022Review
- A Cumulative Framework for Identifying Overburdened Populations under the Toxic Substances Control Act: Formaldehyde Case Study.International journal of environmental research and public health · 2021Article
- Neighborhoods to Nucleotides - Advances and gaps for an obesity disparities systems epidemiology model.Current epidemiology reports · 2019Article
- Article
- Current applications of precision medicine: a bibliometric analysis.Personalized medicine · 2019Review
- The utility of a system dynamics approach for understanding cumulative health risk from exposure to environmental hazards.Environmental research · 2019Article
- Frequency of heavy vehicle traffic and association with DNA methylation at age 18 years in a subset of the Isle of Wight birth cohort.Environmental epigenetics · 2018Article
- DNA methylation of the BRD2 promoter is associated with juvenile myoclonic epilepsy in Caucasians.Epilepsia · 2018Article
- Epigenetics Changes Nothing: What a New Scientific Field Does and Does Not Mean for Ethics and Social Justice.Public health ethics · 2018Article
- Transgenerational epigenetics and environmental justice.Environmental epigenetics · 2017Review
- Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.Environmental health perspectives · 2017Article
- Developmental Origins, Epigenetics, and Equity: Moving Upstream.Maternal and child health journal · 2016Review
- Baseline Chromatin Modification Levels May Predict Interindividual Variability in Ozone-Induced Gene Expression.Toxicological sciences : an official journal of the Society of Toxicology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding differential disease susceptibility requires new tools to quantify the cumulative effects of environmental stress. Evidence suggests that social, physical, and chemical stressors can influence disease through the accumulation of epigenetic modifications. Geographically stable epigenetic alterations could identify plausible mechanisms for health disparities among the disadvantaged and poor. Relations between neighborhood-specific epigenetic markers and disease would identify the most appropriate targets for medical and environmental intervention. Complex interactions among genes, the environment, and disease require the examination of how epigenetic changes regulate susceptibility to environmental stressors. Progress in understanding disparities in disease susceptibility may depend on assessing the cumulative effect of environmental stressors on genetic substrates. We highlight key concepts regarding the interface between environmental stress, epigenetics, and chronic disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.