Evidence map›Paper›PMID 25121440›Full record

ArticleJournal of the Optical Society of America. A, Optics, image science, and vision2014

Rapid computation of the amplitude and phase of tightly focused optical fields distorted by scattering particles.

Janaka C Ranasinghesagara, Carole K Hayakawa, Mitchell A Davis, Andrew K Dunn, Eric O Potma, Vasan Venugopalan

Open access · greenAbstract read
In one paragraph

Article in Journal of the Optical Society of America. A, Optics, image science, and vision, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Modeling nonlinear optical microscopy in scattering media, part I. Propagation from lens to focal volume: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2023
    Article
  2. Modeling nonlinear optical microscopy in scattering media, part II. Radiation from focal volume to far-field: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Janaka C Ranasinghesagara
Carole K Hayakawa
Mitchell A Davis
Andrew K Dunn
Eric O Potma
Vasan Venugopalan
University of California, Irvine · USThe University of Texas at Austin · US

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING · 2012 to 2017
$7.0M
Optical Imaging of Baseline Blood Flow and Oxygenation During StrokeR01EB011556 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K · 2010 to 2018
$3.1M
A Virtual Tissue Simulator for Biomedical OpticsK25EB007309 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI HAYAKAWA, CAROLE KAY · 2008 to 2012
$559k
NIBIB NIH HHS K25 EB007309NIBIB NIH HHS K25-EB007309NIBIB NIH HHS P41 EB015890NIBIB NIH HHS P41-EB015890NIBIB NIH HHS R01 EB011556NIBIB NIH HHS R01-EB011556
6 · The paper itself

Abstract

We develop an efficient method for accurately calculating the electric field of tightly focused laser beams in the presence of specific configurations of microscopic scatterers. This Huygens-Fresnel wave-based electric field superposition (HF-WEFS) method computes the amplitude and phase of the scattered electric field in excellent agreement with finite difference time-domain (FDTD) solutions of Maxwell's equations. Our HF-WEFS implementation is 2-4 orders of magnitude faster than the FDTD method and enables systematic investigations of the effects of scatterer size and configuration on the focal field. We demonstrate the power of the new HF-WEFS approach by mapping several metrics of focal field distortion as a function of scatterer position. This analysis shows that the maximum focal field distortion occurs for single scatterers placed below the focal plane with an offset from the optical axis. The HF-WEFS method represents an important first step toward the development of a computational model of laser-scanning microscopy of thick cellular/tissue specimens.

Indexed as

ArtifactsModels, TheoreticalComputer SimulationImage EnhancementImage Interpretation, Computer-AssistedLightMicroscopy, ConfocalScattering, Radiation

Identifiers

PMID25121440
PMCPMC4213127
OpenAlexW2141560858

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.