ArticlePreventing chronic disease2014
Factors related to coronary heart disease risk among men: validation of the Framingham Risk Score.
Article in Preventing chronic disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Research inefficiencies in external validation studies of the Framingham Wilson coronary heart disease risk rule: A systematic review.PloS one · 2024Pooled it
- Cardiovascular risk factors among adult patients with haemophilia.International journal of hematology · 2021Trial
- A comparison of laboratory-based and office-based Framingham risk scores to predict 10-year risk of cardiovascular diseases: a population-based study.Journal of translational medicine · 2023Article
- The Diagnosis and Management of Cardiometabolic Risk and Cardiometabolic Syndrome after Spinal Cord Injury.Journal of personalized medicine · 2022Review
- Visual functions and disability in Iranian adults: a population-based study.BMC ophthalmology · 2022Article
- The Burden of Cardiovascular Disease Attributable to Modifiable Risk Factors and Cost-effectiveness Analysis of IraPEN Program in the General Population of Iran.Medical journal of the Islamic Republic of Iran · 2022Article
- Food Access and Cardiovascular Outcomes in Metropolitan Atlanta Census Tracts With Residents at Low Risk and High Risk of Cardiovascular Disease: The Morehouse-Emory Cardiovascular Center for Health Equity Study.Preventing chronic disease · 2021Article
- Classification of obesity, cardiometabolic risk, and metabolic syndrome in adults with spinal cord injury.The journal of spinal cord medicine · 2020Article
- Factors influencing left ventricular ejection fraction in patients with coronary microvascular disease and obstructive coronary artery disease.BMC research notes · 2020Observational
- Waist circumference does not improve established cardiovascular disease risk prediction modeling.PloS one · 2020Article
- A Brief Review of Cardiovascular Diseases, Associated Risk Factors and Current Treatment Regimes.Current pharmaceutical design · 2019Review
- Assessing the performance of genome-wide association studies for predicting disease risk.PloS one · 2019Article
- Addition of estimated cardiorespiratory fitness to the clinical assessment of 10-year coronary heart disease risk in asymptomatic men.Preventive medicine reports · 2017Article
- A discriminant analysis prediction model of non-syndromic cleft lip with or without cleft palate based on risk factors.BMC pregnancy and childbirth · 2016Article
- Milk Consumption and Framingham Risk Score: Analysis of the Korea National Health and Nutrition Examination Survey Data (2008-2011).Yonsei medical journal · 2016Article
- Association of Cardiorespiratory Fitness With Coronary Heart Disease in Asymptomatic Men.Mayo Clinic proceedings · 2015Article
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Authors and funding
6 authors.
Funding
Abstract
introductionCoronary heart disease (CHD) remains a leading cause of death in the United States. The Framingham Risk Score (FRS) was developed to help clinicians in determining their patients' CHD risk. We hypothesize that the FRS will be significantly predictive of CHD events among men in the Aerobics Center Longitudinal Study (ACLS) population.
methodsOur study consisted of 34,557 men who attended the Cooper Clinic in Dallas, Texas, for a baseline clinical examination from 1972 through 2002. CHD events included self-reported myocardial infarction or revascularization or death due to CHD. During the 12-year follow-up 587 CHD events occurred. Multivariable-adjusted hazard ratios generated from ACLS analysis were compared with the application of FRS to the Framingham Heart Study (FHS).
resultsThe ACLS cohort produced similar hazard ratios to the FHS. The adjusted Cox proportional hazard model revealed that men with total cholesterol of 280 mg/dL or greater were 2.21 (95% confidence interval (CI), 1.59-3.09) times more likely to have a CHD event than men with total cholesterol from 160 through 199mg/dL; men with diabetes were 1.63 (95% CI, 1.35-1.98) times more likely to experience a CHD event than men without diabetes.
conclusionThe FRS significantly predicts CHD events in the ACLS cohort. To the best of our knowledge, this is the first report of a large, single-center cohort study to validate the FRS by using extensive laboratory and clinical measurements.
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